An ionic liquid {[secbmim]+ Br-} as a "dual reagent catalyst" for the multicomponent synthesis of (quinolinyl- and isoquinolinyl-amino) alkylnaphthols, their bis- analogs and a facile route to naphthoxazines

An atom-economic methodology has been developed for the multi-component one-pot synthesis of (quinolinyl-and isoquinolinyl-amino) alkyl naphthols and their bis- analogs employing the ionic liquid {[(sec)bmim](+) Br-} as a "dual reagent catalysis" at 25 degrees C. The present approach possesses several advantages such as excellent yields, lower reaction times, mild reaction conditions, recyclability and very easy purification processes. The methodology has been further extended towards the facile synthesis of naphthoxazines in very good yields employing formaldehyde in place of aromatic aldehydes.