Synthesis of Benzo[1,2-b:4,5-b']dithiophene and Benzocondensed Thiaheterocycles

被引：2

作者：

Baldoli, Clara ^{[1
]}

Cauteruccio, Silvia ^{[2
]}

Licandro, Emanuela ^{[2
]}

机构：

[1] Natl Res Council CNR, Inst Mol Sci & Technol ISTM, Via C Golgi 19, I-20133 Milan, Italy

[2] Univ Milan, Dipartimento Chim, Via C Golgi 19, I-20133 Milan, Italy

来源：

CHEMISTRYSELECT | 2019年 / 4卷 / 43期

关键词：

benzannulation; benzodithiophene; cycloaromatization; fused-ring systems; sulfur heterocycles; BENZYLIC ALCOHOLS; REDUCTION; RINGS;

D O I：

10.1002/slct.201903811

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A two-step synthesis of benzo[1,2-b:4,5-b']dithiophene (BDT) was carried out starting from 3-thiophene carbaldehyde as the sole thiophene precursor. This method involves the selective lithiation of the 2-position of 3-thiophenecarbaldehyde ethylene acetal, followed by the condensation with 3-thiophenecarbaldehyde and subsequent dehydrative cycloaromatization of the dithienylmethanol intermediate to give BDT. This synthetic pathway was extended to other thiophene benzocondensed heterocycles.

引用

页码：12680 / 12682

页数：3

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