(S)-3-Chloro-4-(4-ethylpiperazin-1-yl)-5-[(1R,2S,5R)-2-isopropyl-5-methylcyclohexyloxy]furan-2(5H)-one

被引:1
|
作者
Fu, Jian-Hua [1 ]
Wang, Zhao-Yang [1 ]
Yang, Kai [1 ]
Mao, Chao-Xu [1 ]
机构
[1] S China Normal Univ, Sch Chem & Environm, Guangzhou 510006, Guangdong, Peoples R China
基金
中国国家自然科学基金;
关键词
D O I
10.1107/S1600536810026929
中图分类号
O7 [晶体学];
学科分类号
0702 ; 070205 ; 0703 ; 080501 ;
摘要
The title compound, C20H33ClN2O3, was obtained via a tandem asymmetric Michael addition-elimination reaction of 3,4-dichloro-5-(S)-(l-menthyloxy)furan-2(5H)-one and 1-ethylpiperazine in the presence of potassium fluoride. The molecular structure contains an approximately planar five-membered furanone ring [maximum atomic deviation = 0.024 (2) A] and two six-membered rings adopting chair conformations. Weak intermolecular C-H...O hydrogen bonding is present in the crystal structure.
引用
收藏
页码:O2022 / U1241
页数:11
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