Methylphenidate does not affect convergent and divergent creative processes in healthy adults

被引:12
作者
Baas, Matthijs [1 ]
Boot, Nathalie [1 ]
van Gaal, Simon [1 ,2 ]
de Dreu, Carsten K. W. [3 ,4 ,5 ]
Cools, Roshan [2 ,6 ]
机构
[1] Univ Amsterdam, Dept Psychol, POB 15919, NL-1001 NK Amsterdam, Netherlands
[2] Donders Inst Brain Cognit & Behav, Ctr Cognit Neuroimaging, Nijmegen, Netherlands
[3] Leiden Univ, Dept Psychol, Leiden, Netherlands
[4] Leiden Univ, Leiden Inst Brain & Cognit, Leiden, Netherlands
[5] Univ Amsterdam, Ctr Expt Econ & Polit Decis Making CREED, Amsterdam, Netherlands
[6] Radboud Univ Nijmegen Med Ctr, Dept Psychiat, Nijmegen, Netherlands
关键词
Creativity; Dopamine; Flexibility; Methylphenidate; ADHD; DEFICIT-HYPERACTIVITY-DISORDER; WORKING-MEMORY; RECEPTOR AVAILABILITY; NOVELTY-SEEKING; DOPAMINE; COGNITION; PREDICTS; MODULATION; PERSONALITY; MODAFINIL;
D O I
10.1016/j.neuroimage.2019.116279
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
An increasing number of healthy people use methylphenidate, a psychostimulant that increases dopamine and noradrenaline transmission in the brain, to help them focus over extended periods of time. While methylphenidate has been shown to facilitate some cognitive functions, like focus and distractor-resistance, the same drug might also contribute to cognitive impairment, for example, in creativity. In this study, we investigated whether acute administration of a low oral dose (20 mg) of methylphenidate affected convergent and divergent creative processes in a sample of young healthy participants. Also, we explored whether such effects depended on individual differences in ADHD symptoms and working memory capacity. Contrary to our expectations, methylphenidate did not affect participants' creative performance on any of the tasks. Also, methylphenidate effects did not depend on individual differences in trait hyperactivity-impulsivity or baseline working memory capacity. Thus, although the effects of methylphenidate on creativity might be underestimated in our study due to several methodological factors, our findings do not suggest that methylphenidate impairs people's ability to be creative.
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页数:9
相关论文
共 90 条
  • [71] The dual pathway to creativity model: Creative ideation as a function of flexibility and persistence
    Nijstad, Bernard A.
    De Dreu, Carsten K. W.
    Rietzschel, Eric F.
    Baas, Matthijs
    [J]. EUROPEAN REVIEW OF SOCIAL PSYCHOLOGY, 2010, 21 : 34 - 77
  • [72] Patton JH, 1995, J CLIN PSYCHOL, V51, P768, DOI 10.1002/1097-4679(199511)51:6<768::AID-JCLP2270510607>3.0.CO
  • [73] 2-1
  • [74] RAPOPORT JL, 1980, ARCH GEN PSYCHIAT, V37, P933
  • [75] Limbic striatal dopamine D2/3 receptor availability is associated with non-planning impulsivity in healthy adults after exclusion of potential dissimulators
    Reeves, Suzanne J.
    Polling, Catherine
    Stokes, Paul R. A.
    Lappin, Julia M.
    Shotbolt, Paul P.
    Mehta, Mitul A.
    Howes, Oliver D.
    Egerton, Alice
    [J]. PSYCHIATRY RESEARCH-NEUROIMAGING, 2012, 202 (01) : 60 - 64
  • [76] Modafinil and methylphenidate for neuroenhancement in healthy individuals: A systematic review
    Repantis, Dimitris
    Schlattmann, Peter
    Laisney, Oona
    Heuser, Isabella
    [J]. PHARMACOLOGICAL RESEARCH, 2010, 62 (03) : 187 - 206
  • [77] Methylphenidate-evoked changes in striatal dopamine correlate with inattention and impulsivity in adolescents with attention deficit hyperactivity disorder
    Rosa-Neto, P
    Lou, HC
    Cumming, P
    Pryds, O
    Karrebaek, H
    Lunding, J
    Gjedde, A
    [J]. NEUROIMAGE, 2005, 25 (03) : 868 - 876
  • [78] Necessity Is the Mother of Invention: Avoidance Motivation Stimulates Creativity Through Cognitive Effort
    Roskes, Marieke
    De Dreu, Carsten K. W.
    Nijstad, Bernard A.
    [J]. JOURNAL OF PERSONALITY AND SOCIAL PSYCHOLOGY, 2012, 103 (02) : 242 - 256
  • [79] The processing-speed theory of adult age differences in cognition
    Salthouse, TA
    [J]. PSYCHOLOGICAL REVIEW, 1996, 103 (03) : 403 - 428
  • [80] A Thalamocorticostriatal Dopamine Network for Psychostimulant-Enhanced Human Cognitive Flexibility
    Samanez-Larkin, Gregory R.
    Buckholtz, Joshua W.
    Cowan, Ronald L.
    Woodward, Neil D.
    Li, Rui
    Ansari, M. Sib
    Arrington, Catherine M.
    Baldwin, Ronald M.
    Smith, Clarence E.
    Treadway, Michael T.
    Kessler, Robert M.
    Zald, David H.
    [J]. BIOLOGICAL PSYCHIATRY, 2013, 74 (02) : 99 - 105