Policy Statement-Postnatal Corticosteroids to Prevent or Treat Bronchopulmonary Dysplasia

被引：172
作者：
Watterberg, Kristi L.
Papile, Lu-Ann
Adamkin, David H.
Baley, Jill E.
Bhutani, Vinod K.
Carlo, Waldemar A.
Kumar, Praveen
Polin, Richard A.
Tan, Rosemarie C.
Wang, Kasper S.
Watterberg, Kristi L.
机构：
来源：
PEDIATRICS | 2010年 / 126卷 / 04期
关键词：
bronchopulmonary dysplasia; preterm infant; glucocorticoid; dexamethasone; chronic lung disease; CHRONIC LUNG-DISEASE; BIRTH-WEIGHT INFANTS; EARLY ADRENAL INSUFFICIENCY; LOW-DOSE DEXAMETHASONE; NEONATAL HYDROCORTISONE TREATMENT; PLACEBO-CONTROLLED TRIAL; PRETERM INFANTS; FOLLOW-UP; RANDOMIZED-TRIAL; SCHOOL-AGE;
D O I：
10.1542/peds.2010-1534
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
The purpose of this revised statement is to review current information on the use of postnatal glucocorticoids to prevent or treat bronchopulmonary dysplasia in the preterm infant and to make updated recommendations regarding their use. High-dose dexamethasone (0.5 mg/kg per day) does not seem to confer additional therapeutic benefit over lower doses and is not recommended. Evidence is insufficient to make a recommendation regarding other glucocorticoid doses and preparations. The clinician must use clinical judgment when attempting to balance the potential adverse effects of glucocorticoid treatment with those of bronchopulmonary dysplasia. Pediatrics 2010;126:800-808
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收藏
页码：800 / 808
页数：9
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