Chromatographic analysis of local anesthetics in biological samples

被引：14
|
作者：
Baniceru, Mihaela [1 ]
Manda, Costel Valentin [1 ]
Popescu, Sanda Mihaela [2 ]
机构：
[1] Univ Med & Pharm, Fac Pharm, Craiova 200349, Romania
[2] Univ Med & Pharm, Fac Med Dent, Craiova 200349, Romania
来源：
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | 2011年 / 54卷 / 01期
关键词：
Gas chromatography; Liquid chromatography; Mass spectrometry; Local anesthetics; Pharmacokinetics; PERFORMANCE LIQUID-CHROMATOGRAPHY; SOLID-PHASE EXTRACTION; TANDEM MASS-SPECTROMETRY; DRUG-PROTEIN BINDING; HUMAN PLASMA; GAS-CHROMATOGRAPHY; HUMAN SERUM; CAPILLARY-ELECTROPHORESIS; ELECTROSPRAY-IONIZATION; DIRECT-INJECTION;
D O I：
10.1016/j.jpba.2010.07.013
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
This paper reviews gas and liquid chromatographic methods for screening, identification and quantification of local anesthetics and/or their metabolites in biological samples. Basic information about sample preparation, separation, detection, and quantification of each procedure is summarised. The pros and cons of the various procedures arc critically discussed. (C) 2010 Elsevier B.V. All rights reserved.
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页码：1 / 12
页数：12
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