Imaging-based approaches to the aggregation-prone mutant huntingtin protein in cellular contexts

被引：0
|
作者：
Sahl, S. J. [1 ]
Vonk, W. I. M. [2 ]
Weiss, L. E. [1 ]
Lau, L. [1 ]
Frydman, J. [2 ]
Moerner, W. E. [1 ]
机构：
[1] Stanford Univ, Dept Chem, Stanford, CA 94305 USA
[2] Stanford Univ, Dept Biol, Stanford, CA 94305 USA
来源：
FEBS JOURNAL | 2014年 / 281卷
关键词：
aggregation-related pathologies; Huntington's disease; Super-resolution microscopy;
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
CS III-4-4
引用
收藏
页码：32 / 32
页数：1
相关论文
共 50 条
  • [21] The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis
    Guthertz, N.
    van Der Kant, R.
    Martinez, R. M.
    Xu, Y.
    Trinh, C.
    Iorga, B. I.
    Rousseau, F.
    Schymkowitz, J.
    Brockwell, D. J.
    Radford, S. E.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2022, 119 (22)
  • [22] Discrimination of soluble and aggregation-prone proteins based on sequence information
    Fang, Yaping
    Fang, Jianwen
    MOLECULAR BIOSYSTEMS, 2013, 9 (04) : 806 - 811
  • [23] The G46S-hPAH mutant protein: A model to study the rescue of aggregation-prone PKU mutations by chaperones
    Leandro, Joao
    Saraste, Jaakko
    Leandro, Paula
    Flatmark, Torgeir
    MOLECULAR GENETICS AND METABOLISM, 2011, 104 : S40 - S44
  • [24] Functional solubilization of aggregation-prone TRAIL protein facilitated by coexpressing with protein isoaspartate methyltranferase
    Zhu, Hu
    Pan, Ruo-Jun
    Wang, Tian-Wen
    Shen, Ya-Ling
    Wei, Dong-Zhi
    APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2006, 72 (05) : 1033 - 1038
  • [25] A comparison of the aggregation of different CFTR-derived peptides, the N-terminal huntingtin fragments and different fusion proteins encompassing the aggregation-prone sequences of CFTR and/or huntingtin
    Bak, D
    Jurkowska, M
    Dolowy, K
    Milewski, M
    FEBS JOURNAL, 2005, 272 : 364 - 365
  • [26] Functional solubilization of aggregation-prone TRAIL protein facilitated by coexpressing with protein isoaspartate methyltranferase
    Hu Zhu
    Ruo-Jun Pan
    Tian-Wen Wang
    Ya-Ling Shen
    Dong-Zhi Wei
    Applied Microbiology and Biotechnology, 2006, 72 : 1033 - 1038
  • [27] MEDI 262-Aggregation and clearance of mutant huntingtin protein
    Rinderspacher, Alison
    Liu, Yidong
    Deng, Shi-Xian
    Gong, Gangli
    Xie, Yuli
    Cremona, M. Laura
    Yamamoto, Ai
    Chung, Caty
    Aulner, Nathalie
    Toebben, Udo
    Vidovic, Dusica
    Schuerer, Stephan
    Smith, Deborah H.
    Branden, Lars
    Rothman, James E.
    Landry, Donald W.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2008, 235
  • [28] Enhancement of ubiquitin conjugating activity promotes the clearance of aggregation-prone mutant proteins in living cells
    Shang, Fu
    Liu, Zhenzhen
    Taylor, Allen
    Zhang, Xinyu
    Wu, Mingxin
    Liu, Yizhi
    Liang, Jack J. N.
    FASEB JOURNAL, 2013, 27
  • [29] Aggregation dynamics and identification of aggregation-prone mutants of the von Hippel-Lindau tumor suppressor protein
    Le Goff, Xavier
    Chesnel, Franck
    Delalande, Olivier
    Couturier, Anne
    Dreano, Stephane
    Le Goff, Cathy
    Vigneau, Cecile
    Arlot-Bonnemains, Yannick
    JOURNAL OF CELL SCIENCE, 2016, 129 (13) : 2638 - 2650
  • [30] Archaeal proteasomes effectively degrade aggregation-prone proteins and reduce cellular toxicities in mammalian cells
    Yamada, Shin-ichi
    Niwa, Jun-ichi
    Ishigaki, Shinsuke
    Takahashi, Miho
    Ito, Takashi
    Sone, Jun
    Doyu, Manabu
    Sobue, Gen
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (33) : 23842 - 23851
12345