Climatotherapy at the Dead Sea: An Effective Treatment Modality for Atopic Dermatitis With Significant Positive Impact on Quality of Life

被引:27
作者
Adler-Cohen, Chagit [1 ,2 ,3 ,4 ]
Czarnowicki, Tali [1 ,2 ,3 ,4 ]
Dreiher, Jacob [5 ]
Ruzicka, Thomas [1 ,2 ,3 ,4 ]
Ingber, Arieh [1 ,2 ,3 ,4 ]
Harari, Marco [1 ,2 ,3 ,4 ]
机构
[1] Hadassah Univ Med Ctr, RIDS Joint Res Inst Climatotherapy Skirt Dis Dead, Jerusalem, Israel
[2] Hadassah Univ Med Ctr, Deutsch Med Zentrum Med Ctr, Jerusalem, Israel
[3] Hadassah Univ Med Ctr, Dept Dermatol, Jerusalem, Israel
[4] Ludwig Maximilian Univ Hosp, Dept Dermatol, Munich, Germany
[5] Ben Gurion Univ Negev, Siaal Res Ctr, Div Hlth Commun, IL-84105 Beer Sheva, Israel
关键词
NARROW-BAND UVB; CHILDHOOD; PHOTOTHERAPY; SEVERITY; SAFETY; FAMILY; BALNEOPHOTOTHERAPY; PSORIASIS; SYMPTOMS; SKINDEX;
D O I
10.1097/DER.0b013e31824a6141
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Background: Atopic dermatitis (AD) has an appreciable effect on quality of life. Improving the quality of life of AD patients is a priority. Objective: This study aimed to evaluate the impact of Dead Sea climatotherapy (DSC) as a treatment of AD and its influence on the quality of life of these patients. Methods: Forty-nine adult patients with AD treated during the years 2009-2010 at the Deutsches Medizinisches Zentrum Medical Center participated in this prospective study. Climatotherapy was administered in accordance with a computer-designed protocol and included gradually increased sun exposure after a sea bath. Severity of AD was evaluated using the Scoring Atopic Dermatitis (SCORAD) index. Patient quality of life was evaluated using Skindex-29. Statistical analysis was performed using a paired t test and Wilcoxon and Mann-Whitney U tests. Results: After treatment, the mean SCORAD value improved by 39 points (P < 0.001). The overall Skindex-29 score improved by a mean value of 33 points (P < 0.001). The pretreatment SCORAD, duration of AD, and maximal daily sun exposure predicted the posttreatment SCORAD values. Pretreatment Skindex-29 and patient age predicted the posttreatment Skindex-29 in a multiple linear regression model. Conclusions: Dead Sea climatotherapy provides an effective treatment modality for AD by improving the patient's skin condition and quality of life.
引用
收藏
页码:75 / 80
页数:6
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