Inhibitors targeting two-component signal transduction

被引:0
|
作者
Watanabe, Takafumi [1 ]
Okada, Ario [1 ]
Gotoh, Yasuhiro [1 ]
Utsumi, Ryutaro [1 ]
机构
[1] Kinki Univ, Grad Sch Agr, Dept Biosci, Nara 6318505, Japan
来源
BACTERIAL SIGNAL TRANSDUCTION: NETWORKS AND DRUG TARGETS | 2008年 / 631卷
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暂无
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
A two-component signal transduction system (TCS) is an attractive target for antibacterial agents. In this chapter, we review the TCS inhibitors developed during the past decade and introduce novel drug discovery systems to isolate the inhibitors of the YycG/YycF system, an essential TCS for bacterial growth, in an effort to develop a new class of antibacterial agents.
引用
收藏
页码:229 / 236
页数:8
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