Vectorial Release of Human RNA Viruses from Epithelial Cells

被引：1

作者：

Chapuy-Regaud, Sabine ^{[1
,2
]}

Allioux, Claire ^{[2
]}

Capelli, Nicolas ^{[1
,2
,3
]}

Migueres, Marion ^{[1
,2
]}

Lhomme, Sebastien ^{[1
,2
]}

Izopet, Jacques ^{[1
,2
]}

机构：

[1] CHU Purpan, Dept Virol, F-31059 Toulouse, France

[2] Univ Toulouse III, INFINITy Toulouse Inst Infect & Inflammatory Dis, INSERM UMR1291, CNRS UMR5051,CHU Purpan, F-31024 Toulouse, France

[3] Catholic Univ Louvain, VIRO Unit, B-1020 Brussels, Belgium

来源：

VIRUSES-BASEL | 2022年 / 14卷 / 02期

关键词：

human RNA virus; epithelium; polarization; release or egress; HEPATITIS-C VIRUS; BASOLATERAL PLASMA-MEMBRANE; RECYCLING ENDOSOMES; VIRAL GLYCOPROTEIN; APICAL MEMBRANE; POLARIZED ENTRY; MARBURG VIRUS; A VIRUS; INFECTION; TRANSPORT;

D O I：

10.3390/v14020231

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Epithelial cells are apico-basolateral polarized cells that line all tubular organs and are often targets for infectious agents. This review focuses on the release of human RNA virus particles from both sides of polarized human cells grown on transwells. Most viruses that infect the mucosa leave their host cells mainly via the apical side while basolateral release is linked to virus propagation within the host. Viruses do this by hijacking the cellular factors involved in polarization and trafficking. Thus, understanding epithelial polarization is essential for a clear understanding of virus pathophysiology.

引用

页数：15

共 131 条

[1] Role of membrane traffic in the generation of epithelial cell asymmetry [J].

Apodaca, Gerard ;

Gallo, Luciana I. ;

Bryant, David M. .

NATURE CELL BIOLOGY, 2012, 14 (12) :1235-1243

[2]

Awad A, 2017, WORLD J HEPATOL, V9, P18, DOI 10.4254/wjh.v9.i1.18

[3] FSHIP2 regulates epithelial cell polarity through its lipid product, which binds to Dlg1, a pathway subverted by hepatitis C virus core protein [J].

Awad, Aline ;

Sar, Sokhavuth ;

Barre, Ronan ;

Cariven, Clotilde ;

Marin, Mickael ;

Salles, Jean Pierre ;

Erneux, Christophe ;

Samuel, Didier ;

Gassama-Diagne, Ama .

MOLECULAR BIOLOGY OF THE CELL, 2013, 24 (14) :2171-2185

[4] Entry and Release of Hepatitis C Virus in Polarized Human Hepatocytes [J].

Belouzard, Sandrine ;

Danneels, Adeline ;

Feneant, Lucie ;

Seron, Karin ;

Rouille, Yves ;

Dubuisson, Jean .

JOURNAL OF VIROLOGY, 2017, 91 (18)

[5] Infection of polarized cultures of human intestinal epithelial cells with hepatitis A virus: Vectorial release of progeny virions through apical cellular membranes [J].

Blank, CA ;

Anderson, DA ;

Beard, M ;

Lemon, SM .

JOURNAL OF VIROLOGY, 2000, 74 (14) :6476-6484

[6] Polarity of human parainfluenza virus type 3 infection in polarized human lung epithelial A549 cells: Role of microfilament and microtubule [J].

Bose, S ;

Malur, A ;

Banerjee, AK .

JOURNAL OF VIROLOGY, 2001, 75 (04) :1984-1989

[7] The Rab11 Pathway Is Required for Influenza A Virus Budding and Filament Formation [J].

Bruce, Emily A. ;

Digard, Paul ;

Stuart, Amanda D. .

JOURNAL OF VIROLOGY, 2010, 84 (12) :5848-5859

[8] Long-term differentiating primary human airway epithelial cell cultures: how far are we? [J].

Bukowy-Bieryllo, Zuzanna .

CELL COMMUNICATION AND SIGNALING, 2021, 19 (01)

[9] Growth of Zika virus in human reconstituted respiratory, intestinal, vaginal and neural tissues [J].

Cagno, V. ;

Tseligka, E. D. ;

Bettex, Q. ;

Huang, S. ;

Constant, S. ;

Tapparel, C. .

CLINICAL MICROBIOLOGY AND INFECTION, 2019, 25 (08) :1042.e1-1042.e4

[10] Optimized Hepatitis E Virus (HEV) Culture and Its Application to Measurements of HEV Infectivity [J].

Capelli, Nicolas ;

Dubois, Martine ;

Pucelle, Melanie ;

Da Silva, Isabelle ;

Lhomme, Sebastien ;

Abravanel, Florence ;

Chapuy-Regaud, Sabine ;

Izopet, Jacques .

VIRUSES-BASEL, 2020, 12 (02)

← 1 2 3 4 5 6 7 8 9 10 →