Facile route to functionalized mesoporous silica nanoparticles by click chemistry

被引：44

作者：

Moitra, Nirmalya ^{[1
]}

Trens, Philippe ^{[1
]}

Raehm, Laurence ^{[1
]}

Durand, Jean-Olivier ^{[1
]}

Cattoen, Xavier ^{[1
]}

Man, Michel Wong Chi ^{[1
]}

机构：

[1] Inst Charles Gerhardt Montpellier, CNRS, ENSCM, UMR 5253,UM2,UM1, F-34095 Montpellier 05, France

来源：

JOURNAL OF MATERIALS CHEMISTRY | 2011年 / 21卷 / 35期

关键词：

RELEASE DRUG-DELIVERY; MOLECULAR MACHINES; CANCER-CELLS; SYSTEM; NANOCONTAINERS; AGENTS;

D O I：

10.1039/c1jm12066b

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Mesoporous silica nanoparticles containing clickable functions (azide or alkyne, 1 or 10 mol%) were synthesized by the sol-gel method directly from molecular precursors using CTAB as structure directing agent. Their structures were discussed on the basis of TEM, DLS, SAXS, N(2)-sorption analyses, FTIR, Raman and elemental analysis. The success of their functionalization by pyrene derivatives using CuAAC reactions opens new perspectives in the synthesis of functional MSNs for applications as nanomachines.

引用

页码：13476 / 13482

页数：7

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