Synthesis of Glycosylated Metal Complexes for Probing Carbohydrate-Carbohydrate Interactions

被引:1
|
作者
Hasegawa, Teruaki [1 ,2 ]
机构
[1] Toyo Univ, Fac Life Sci, Itakura, Gunma, Japan
[2] Toyo Univ, Bionano Elect Res Ctr, Kawagoe, Saitama, Japan
来源
GLYCOBIOPHYSICS | 2018年 / 1104卷
关键词
Carbohydrate-carbohydrate interactions; Tris-bipyridine ferrous complex; Dynamic combinatorial library; Circular dichroism; GOLD GLYCONANOPARTICLES; CELL-ADHESION; RECOGNITION; HELIX; MODEL;
D O I
10.1007/978-981-13-2158-0_2
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Densely packed carbohydrate clusters on cell surfaces play essential roles in varieties of bioprocesses. Little information has been, however, accumulated so far concerning their structural/functional details. In this chapter, we discuss artificial systems to investigate carbohydrate-carbohydrate interactions within/between the carbohydrate cluster(s). Among such artificial systems, much attention will be especially placed on glycosylated tris-bipyridine ferrous complexes for monitoring not only carbohydrate-carbohydrate interactions within the glycocluster but also their resultant conformational changes.
引用
收藏
页码:21 / 39
页数:19
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