Preparation of thioamides from alkyl bromides, nitriles, and hydrogen sulfide through a thio-Ritter-type reaction

被引：2

作者：

Tang, Shi-Zhong ^{[1
,2
]}

Xiang, Kai ^{[3
]}

Ye, Rui ^{[1
,2
]}

Chen, Meng-En ^{[1
,2
]}

Yu, Jian-Chang ^{[1
,2
]}

He, Zhi-Juan ^{[1
,2
]}

Zhang, Fu-Min ^{[1
,2
]}

机构：

[1] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China

[2] Lanzhou Univ, Coll Chem & Chem Engn, Lanzhou 730000, Peoples R China

[3] Beijing Inst Aerosp Testing Technol, Beijing Key Lab Res & Applicat Aerosp Green Prope, Beijing 100074, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2022年 / 58卷 / 81期

关键词：

AMIDES; ARYLATION; REAGENT; HALIDES; SULFUR; IONS;

D O I：

10.1039/d2cc04210j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel thio-Ritter-type reaction of alkyl bromides, nitriles, and hydrogen sulfide has been explored, providing a straightforward approach toward functionally important thioamides. This transformation features a broad substrate scope, operational simplicity, use of available feedstock chemicals, and late-stage functionalizations of bioactive molecules. The reaction mechanism is also proposed.

引用

页码：11430 / 11433

页数：4

共 20 条

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Cai, Tian-cheng
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Jinzhou Petrochemical Co, Jinzhou, China
Huagong Xuebao, 4 (447-452):
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