Reductive sulfur extrusion reaction of 2,1,3-benzothiadiazole compounds:: a new methodology using NaBH4/CoCl2•6H2O(cat) as the reducing system

被引：67

作者：

Neto, BAD ^{[1
]}

Lopes, AS ^{[1
]}

Wüst, M ^{[1
]}

Costa, VEU ^{[1
]}

Ebeling, G ^{[1
]}

Dupont, J ^{[1
]}

机构：

[1] Univ Fed Rio Grande do Sul, Dept Quim Organ, Lab Mol Catalysis, Inst Quim, BR-91501970 Porto Alegre, RS, Brazil

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 40期

关键词：

sulfur extrusion; benzothiadiazole;

D O I：

10.1016/j.tetlet.2005.08.017

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new simple and efficient methodology for reductive sulfur extrusion from 2,1,3-benzothiadiazole compounds has been developed using NaBH4 in the presence of catalytic amounts of ClCl2-6H(2)O (1 mol %). This method is an efficient alternative for the generation of various 1,4-disubstituted-2,3-diaminobenzene derivatives from 4,7-disubstituted-2,1,3-benzothiadiazoles. The diamines can be easily converted into 4,7-disubstitttted-quinoxaline compounds by simple reaction with glyoxal-sodium bisulfite. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：6843 / 6846

页数：4

共 31 条

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