Stereoselective Total Synthesis of Stagonolide E

被引：5

作者：

Rajaram, Singanaboina ^{[1
]}

Ramulu, Udugu ^{[1
]}

Aravind, Seema ^{[1
]}

Babu, Katragadda Suresh ^{[1
]}

机构：

[1] CSIR Indian Inst Chem Technol, Div Nat Prod Chem, Hyderabad 500007, Andhra Pradesh, India

来源：

HELVETICA CHIMICA ACTA | 2015年 / 98卷 / 05期

关键词：

HornerWadsworthEmmons olefination; MacMillan; -hydroxylation; Stagonolide E; Yamaguchi lactonization; StillGennari olefination; ENANTIOSELECTIVE SYNTHESIS; STAGONOSPORA-CIRSII; EMMONS OLEFINATION; ALDEHYDES; ALCOHOLS;

D O I：

10.1002/hlca.201400265

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient and highly stereoselective synthesis of stagonolide E (1) starting from the readily available hexane-1,6-diol (8) was accomplished, employing MacMillan -hydroxylation, Horner WadsworthEmmons olefination, (Z)-selective StillGennari olefination, and Yamaguchi lactonization as key steps.

引用

页码：650 / 656

页数：7

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