Vulvar melanoma:: a report of 10 cases and review of the literature

被引:31
作者
De Simone, Paola [1 ]
Silipo, Vitaliano [1 ]
Buccini, Pierluigi [1 ]
Mariani, Giustino [1 ]
Marenda, Samantha [1 ]
Eibenschutz, Laura [1 ]
Ferrari, Angela [1 ]
Catricalca, Caterina [1 ]
机构
[1] San Gallicano Dermatol Inst IFO, Dept Dermatol Oncol, Rome, Italy
关键词
malignant melanoma; vulvar melanoma; vulvar neoplasm;
D O I
10.1097/CMR.0b013e3282f94636
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Despite its low incidence, vulvar melanoma carries a poor prognosis and shows a high tendency to metastasize because the diagnosis is often delayed. Although it is very well known that ultraviolet radiation is an important aetiological factor for cutaneous melanomas in adults, this cannot be considered true for vulvar melanoma. Chronic inflammatory disease, viral infections, irritant agents are the main factors suspected to induce mucosal melanoma. We report 10 cases of vulvar malignant melanoma observed in our institute from 1990 to 2005 and a review of the literature.
引用
收藏
页码:127 / 133
页数:7
相关论文
共 32 条
[1]   Synchronous cervical and vulvar malign melanomas: metastasis or multifocality of the disease? A case report and review of the literature [J].
Akoz, I ;
Ayas, S ;
Eren, S ;
Bilgic, R .
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2006, 16 (02) :917-U6
[2]   Vulvar melanoma: Diffuse melanosis and metastasis to the placenta [J].
Alexander, A ;
Harris, RM ;
Grossman, D ;
Bruggers, CS ;
Leachman, SA .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2004, 50 (02) :293-298
[3]   EFFICACY OF 2-CM SURGICAL MARGINS FOR INTERMEDIATE-THICKNESS MELANOMAS (1 TO 4 MM) - RESULTS OF A MULTIINSTITUTIONAL RANDOMIZED SURGICAL TRIAL [J].
BALCH, CM ;
URIST, MM ;
KARAKOUSIS, CP ;
SMITH, TJ ;
TEMPLE, WJ ;
DRZEWIECKI, K ;
JEWELL, WR ;
BARTOLUCCI, AA ;
MIHM, MC ;
BARNHILL, R ;
WANEBO, HJ .
ANNALS OF SURGERY, 1993, 218 (03) :262-269
[4]  
BRAGDATA MG, 1990, BRIT J OBSTET GYNAEC, V97, P124
[5]  
Chang AE, 1998, CANCER, V83, P1664, DOI 10.1002/(SICI)1097-0142(19981015)83:8<1664::AID-CNCR23>3.0.CO
[6]  
2-G
[7]   MALIGNANT-MELANOMA OF VULVA - REPORT OF 44 CASES [J].
CHUNG, AF ;
WOODRUFF, JM ;
LEWIS, JL .
OBSTETRICS AND GYNECOLOGY, 1975, 45 (06) :638-646
[8]  
CULLEN W, 1824, T MED CHIR SOC EDINB, P264
[9]  
DAHAR KK, 2005, BJOG, V112, P696
[10]  
de Hullu JA, 1998, J NUCL MED, V39, P1381