Antioxidant Potential and In Situ Analysis of Major and Trace Element Determination of Ood-saleeb, a Known Unani Herbal Medicine by ICP-MS

被引:11
作者
Raish, Mohammad [1 ]
Ahmad, Ajaz [2 ]
Alkharfy, Khalid M. [2 ]
Al-Jenoobi, Fahad I. [1 ]
Al-Mohizea, Abdullah M. [1 ]
Mohsin, Kazi [1 ]
Ahamad, Syed Rizwan [3 ]
Ali, Naushad [4 ]
Shakeel, Faiyaz [1 ,5 ]
机构
[1] King Saud Univ, Coll Pharm, Dept Pharmaceut, POB 2457, Riyadh 11451, Saudi Arabia
[2] King Saud Univ, Dept Clin Pharm, Coll Pharm, Riyadh 11451, Saudi Arabia
[3] King Saud Univ, Coll Pharm, Res Ctr, Riyadh 11451, Saudi Arabia
[4] King Saud Univ, Coll Pharm, Qual Assurance Unit, Riyadh 11451, Saudi Arabia
[5] King Saud Univ, CEBR, Riyadh 11451, Saudi Arabia
关键词
Antioxidant; Ascorbic acid; Ood-saleeb; Trace elements; ICP-MS; RADICAL SCAVENGING ACTIVITIES; PLASMA; BORON; ZINC; DEFICIENCY; EXTRACTION; PREVENTION; CAPACITY; HEALTH; INDICA;
D O I
10.1007/s12011-015-0607-x
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The intention of the present research work was to investigate the antioxidant activity and trace element analysis of Ood-saleeb, a known herbal medicine. Preliminary screening of phytochemicals showed that the extract of Ood-saleeb had flavonoids and phenolics. The significant activities in all antioxidant assays were observed in the extract of Ood-saleeb in comparison with the standard antioxidant with respect to dose of Ood-saleeb. Incredible activities to scavenge reactive oxygen species were also observed by the extract of Ood-saleeb. The IC50 values of all factors were determined using ascorbic acid as a standard. The inductive coupled plasmamass spectroscopy (ICP-MS) was employed for the estimation of trace elements in Ood-saleeb extract. The concentrations of up to 18 elements were detected successfully. Silicon was found in high concentration (85.3 mu g/g) while lithium was in low concentration (3 ng/g). The trace elements in the sample were found at different percentage levelswhich play a key role in the treatment of diseases.
引用
收藏
页码:521 / 527
页数:7
相关论文
共 52 条
  • [1] Abbas A., 2012, Journal of King Saud University-Engineering Sciences, V24, P159, DOI [10.1016/j.jksues.2011.10.003, DOI 10.1016/J.JKSUES.2011.10.003]
  • [2] Application of Box-Behnken design for ultrasonic-assisted extraction of polysaccharides from Paeonia emodi
    Ahmad, Ajaz
    Alkharfy, Khalid M.
    Wani, Tanveer A.
    Raish, Mohammad
    [J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2015, 72 : 990 - 997
  • [3] Ahmed T, 2010, CLIN INTERV AGING, V5, P207
  • [4] Amir M, 2011, FREE RADIC ANTIOXID, V1, P75, DOI [DOI 10.5530/AX.2011.4.12, 10.5530/ax.2011.4.12]
  • [5] Calcium, phosphorus and human bone development
    Anderson, JJB
    [J]. JOURNAL OF NUTRITION, 1996, 126 (04) : S1153 - S1158
  • [6] [Anonymous], 2011, INT J BIOSCI
  • [7] In vivo and in vitro effects of boron and boronated compounds
    Benderdour, M
    Bui-Van, T
    Dicko, A
    Belleville, F
    [J]. JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY, 1998, 12 (01) : 2 - 7
  • [8] Brini Marisa, 2013, Met Ions Life Sci, V13, P81, DOI 10.1007/978-94-007-7500-8_4
  • [9] Zinc in plants
    Broadley, Martin R.
    White, Philip J.
    Hammond, John P.
    Zelko, Ivan
    Lux, Alexander
    [J]. NEW PHYTOLOGIST, 2007, 173 (04) : 677 - 702
  • [10] Campbell NA, 1987, BIOLOGY, P1230