Comparative genomics provides insights into the aquatic adaptations of mammals

被引：72

作者：

Yuan, Yuan ^{[1
,2
]}

Zhang, Yaolei ^{[3
,4
,5
]}

Zhang, Peijun ^{[1
]}

Liu, Chang ^{[2
]}

Wang, Jiahao ^{[3
,6
]}

Gao, Haiyu ^{[1
]}

Hoelzel, A. Rus ^{[7
]}

Seim, Inge ^{[8
,9
]}

Lv, Meiqi ^{[3
]}

Lin, Mingli ^{[1
]}

Dong, Lijun ^{[1
]}

Gao, Haoyang ^{[3
]}

Yang, Zixin ^{[1
]}

Caruso, Francesco ^{[1
]}

Lin, Wenzhi ^{[1
]}

da Fonseca, Rute R. ^{[10
]}

Wang, Ding ^{[11
]}

Wang, Xianyan ^{[12
]}

Rasmussen, Marianne H. ^{[13
]}

Liu, Mingming ^{[1
]}

Zheng, Jinsong ^{[11
]}

Zhao, Liyuan ^{[12
]}

Campos, Paula F. ^{[14
]}

Kang, Hui ^{[1
]}

Iversen, Maria ^{[13
]}

Song, Yue ^{[3
]}

Guo, Xinyu ^{[3
]}

Guo, Jiao ^{[3
]}

Qin, Yating ^{[3
]}

Pan, Shanshan ^{[3
]}

Xu, Qiwu ^{[3
]}

Meng, Lingfeng ^{[3
]}

Yunga, A. ^{[3
]}

Liu, Shanshan ^{[3
]}

Lee, Simon Ming-Yuen ^{[15
]}

Liu, Xin ^{[3
,4
,6
]}

Xu, Xun ^{[4
]}

Yang, Huanming ^{[4
]}

Fan, Guangyi ^{[3
,4
,6
,15
]}

Wang, Kun ^{[2
]}

Li, Songhai ^{[1
,16
,17
]}

机构：

[1] Chinese Acad Sci, Inst Deep Sea Sci & Engn, Marine Mammal & Marine Bioacoust Lab, Sanya 572000, Peoples R China

[2] Northwestern Polytech Univ, Sch Ecol & Environm, Xian 710072, Peoples R China

[3] BGI Shenzhen, BGI Qingdao, Qingdao 266555, Peoples R China

[4] BGI Shenzhen, Shenzhen 518083, Peoples R China

[5] Tech Univ Denmark, Dept Biotechnol & Biomed, DK-2800 Lyngby, Denmark

[6] BGI Shenzhen, State Key Lab Agr Genom, Shenzhen 518083, Peoples R China

[7] Univ Durham, Dept Biosci, Durham DH1 3LE, England

[8] Nanjing Normal Univ, Coll Life Sci, Integrat Biol Lab, Nanjing 210046, Peoples R China

[9] Queensland Univ Technol, Sch Biol & Environm Sci, Brisbane, Qld 4000, Australia

[10] Univ Copenhagen, Globe Inst, Ctr Macroecol Evolut & Climate, DK-1165 Copenhagen, Denmark

[11] Chinese Acad Sci, Key Lab Aquat Biodivers & Conservat, Inst Hydrobiol, Wuhan 430072, Peoples R China

[12] Minist Nat Resources, Lab Marine Biol & Ecol, Inst Oceanog 3, Xiamen 361005, Peoples R China

[13] Univ Iceland, Res Ctr Husavik, IS-640 Husavik, Iceland

[14] Univ Porto, Interdisciplinary Ctr Marine & Environm Res, P-4450208 Matosinhos, Portugal

[15] Univ Macau, Inst Chinese Med Sci, State Key Lab Qual Res Chinese Med, Macau 999078, Peoples R China

[16] Natl Univ Singapore, Trop Marine Sci Inst, Singapore 119227, Singapore

[17] Chinese Acad Sci, Ctr Ocean Megasci, Qingdao 266071, Peoples R China

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 2021年 / 118卷 / 37期

基金：

中国国家自然科学基金; 新加坡国家研究基金会;

关键词：

marine mammals; comparative genomics; aquatic adaptation; INNER-EAR PROTEIN; SPERM-WHALES; BROWN FAT; EVOLUTION; TRANSITIONS; RESOLUTION; ADMIXTURE; POLAR; GAMMA; XYLT1;

D O I：

10.1073/pnas.2106080118

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The ancestors of marine mammals once roamed the land and independently committed to an aquatic lifestyle. These macroevolutionary transitions have intrigued scientists for centuries. Here, we generated high-quality genome assemblies of 17 marine mammals (11 cetaceans and six pinnipeds), including eight assemblies at the chromosome level. Incorporating previously published data, we reconstructed the marine mammal phylogeny and population histories and identified numerous idiosyncratic and convergent genomic variations that possibly contributed to the transition from land to water in marine mammal lineages. Genes associated with the formation of blubber (NFIA), vascular development (SEMA3E), and heat production by brown adipose tissue (UCP1) had unique changes that may contribute to marine mammal thermoregulation. We also observed many lineage-specific changes in the marine mammals, including genes associated with deep diving and navigation. Our study advances understanding of the timing, pattern, and molecular changes associated with the evolution of mammalian lineages adapting to aquatic life.

引用

页数：9

共 90 条

[1]

Baird Robin W., 2005, Pacific Science, V59, P461, DOI 10.1353/psc.2005.0031

[2] Homozygous deletion of EPB41 genuine AUG-containing exons results in mRNA splicing defects, NMD activation and protein 4.1R complete deficiency in hereditary elliptocytosis [J].

Baklouti, Faouzi ;

Moriniere, Madeleine ;

Haj-Khelil, Amel ;

Feneant-Thibault, Madeleine ;

Gruffat, Henri ;

Coute, Yohann ;

Ninot, Alain ;

Guitton, Corinne ;

Delaunay, Jean .

BLOOD CELLS MOLECULES AND DISEASES, 2011, 47 (03) :158-165

[3] A bit of give and take: the relationship between the extracellular matrix and the developing chondrocyte [J].

Behonick, DJ ;

Werb, Z .

MECHANISMS OF DEVELOPMENT, 2003, 120 (11) :1327-1336

[4]

Berta A, 2012, RETURN TO THE SEA: THE LIFE AND EVOLUTIONARY TIMES OF MARINE MAMMALS, P1, DOI 10.1525/california/9780520270572.001.0001

[5]

Berta A., 2005, Marine mammals: evolutionary biology

[6] RELATIVE ABUNDANCE OF CETACEA IN THE CANAL-DE-BALLENAS, GULF OF CALIFORNIA [J].

BREESE, D ;

TERSHY, BR .

MARINE MAMMAL SCIENCE, 1993, 9 (03) :319-324

[7]

Buenrostro JD, 2013, NAT METHODS, V10, P1213, DOI [10.1038/NMETH.2688, 10.1038/nmeth.2688]

[8] XYLT1 Mutations in Desbuquois Dysplasia Type 2 [J].

Bui, Catherine ;

Huber, Celine ;

Tuysuz, Beyhan ;

Alanay, Yasemin ;

Bole-Feysot, Christine ;

Leroy, Jules G. ;

Mortier, Geert ;

Nitschke, Patrick ;

Munnich, Arnold ;

Cormier-Daire, Valerie .

AMERICAN JOURNAL OF HUMAN GENETICS, 2014, 94 (03) :405-414

[9] Genomic Evidence of Widespread Admixture from Polar Bears into Brown Bears during the Last Ice Age [J].

Cahill, James A. ;

Heintzman, Peter D. ;

Harris, Kelley ;

Teasdale, Matthew D. ;

Kapp, Joshua ;

Soares, Andre E. R. ;

Stirling, Ian ;

Bradley, Daniel ;

Edwards, Ceiridwen J. ;

Graim, Kiley ;

Kisleika, Aliaksandr A. ;

Malev, Alexander, V ;

Monaghan, Nigel ;

Green, Richard E. ;

Shapiro, Beth .

MOLECULAR BIOLOGY AND EVOLUTION, 2018, 35 (05) :1120-1129

[10]

Castellini M, 2006, BIORHEOLOGY, V43, P57

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