Cryptococcal immune reconstitution syndrome during steroid withdrawal treated with hydroxychloroquine

被引:19
作者
Narayanan, Shivakumar [1 ]
Banerjee, Chandralekha [2 ]
Holt, Peter A. [3 ]
机构
[1] Good Samaritan Hosp Maryland, Dept Internal Med, RMB, Baltimore, MD 21239 USA
[2] Good Samaritan Hosp Maryland, Div Infect Dis, Dept Internal Med, Baltimore, MD 21239 USA
[3] Good Samaritan Hosp Maryland, Div Rheumatol, Dept Internal Med, Baltimore, MD 21239 USA
关键词
Cryptococcosis; Immune reconstitution syndrome; Steroid withdrawal; Hypercalcemia; Skin nodules; Hydroxychloroquine; CHLOROQUINE; INFECTION; HYPERCALCEMIA; NEOFORMANS; ALPHA;
D O I
10.1016/j.ijid.2010.09.006
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
We present a case report of cryptococcal immune reconstitution syndrome (IRS), in a non HIV infected patient, which we treated with hydroxychloroquine with successful results. We briefly review cryptococcal IRS, possible mechanisms of action of hydroxychloroquine as an immunomodulatory agent, and its potential role in management of IRS. (C) 2010 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:E70 / E73
页数:4
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