DYNLL1 INHIBITS DNA END RESECTION IN BRCA1-DEFICIENT CELLS AND REGULATES PARP INHIBITOR SENSITIVITY

被引：0
|
作者：
He, Yizhou Joseph [1 ]
Meghani, Khyati [1 ]
Caron, Marie-Christine [2 ,3 ]
Yang, Chunyu [1 ]
Ronato, Daryl A. [2 ,3 ]
Bian, Jie [1 ]
Sharma, Anchal [4 ]
Miller, Jessica [1 ]
Joshi, Niraj [1 ]
Detappe, Alexandre [5 ]
Doench, John G. [6 ]
Legube, Gaelle [7 ]
Root, David E. [6 ]
D'Andrea, Alan D. [1 ,8 ]
Drane, Pascal [1 ]
De, Subhojyoti [4 ]
Konstantinopoulos, Panagiotis [5 ]
Masson, Jean-Yves [2 ,3 ]
Chowdhury, Dipanjan [1 ,6 ,9 ]
机构：
[1] Harvard Med Sch, Dana Farber Canc Inst, Dept Radiat Oncol, Div Radiat & Genome Stabil, Boston, MA 02215 USA
[2] CHU Quebec Res Ctr, Genome Stabil Lab, Oncol Axis, HDQ Pavil,9 McMahon, Quebec City, PQ G1R 2J6, Canada
[3] Laval Univ, Canc Res Ctr, Dept Mol Biol Med Biochem & Pathol, Quebec City, PQ G1V 0A6, Canada
[4] Rutgers Canc Inst New Jersey, New Brunswick, NJ USA
[5] Harvard Med Sch, Dana Farber Canc Inst, Dept Med Oncol, Boston, MA 02215 USA
[6] Broad Inst MIT & Harvard, Cambridge, MA 02142 USA
[7] Univ Toulouse, CNRS, CBI, LBCMCP,UT3, 118 Route Narbonne, F-31062 Toulouse, France
[8] Harvard Med Sch, Dana Farber Canc Inst, Ctr DNA Damage & Repair, Boston, MA 02215 USA
[9] Harvard Med Sch, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA
来源：
CLINICAL CANCER RESEARCH | 2019年 / 25卷 / 22期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
GMM-027
引用
收藏
页码：90 / 90
页数：1
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