Complete Genome Sequence of Adherent Invasive Escherichia coli UM146 Isolated from Ileal Crohn's Disease Biopsy Tissue

被引:50
作者
Krause, Denis O. [1 ,2 ]
Little, Ainsley C. [1 ]
Dowd, Scot E. [4 ]
Bernstein, Charles N. [3 ]
机构
[1] Univ Manitoba, Dept Anim Sci, Winnipeg, MB R3T 2N2, Canada
[2] Univ Manitoba, Dept Med Microbiol, Winnipeg, MB R3T 2N2, Canada
[3] Univ Manitoba, Dept Internal Med, Winnipeg, MB R3T 2N2, Canada
[4] Res & Testing Lab, Lubbock, TX 79407 USA
关键词
INFLAMMATORY-BOWEL-DISEASE; STRAIN;
D O I
10.1128/JB.01290-10
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Escherichia coli UM146 was isolated from the ileum of a Crohn's disease patient. It adheres to and invades enterocytes and can replicate inside macrophages. Its complete genome sequence reveals that it is most closely related to the human urinary tract pathogen E. coli CFT073, but it has a host of genes that are novel and to which no function has been ascribed.
引用
收藏
页码:583 / 583
页数:1
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