A new beta-carboline alkaloid isolated from the marine sponge Hyrtios erecta

被引:50
作者
BourguetKondracki, ML [1 ]
Martin, MT [1 ]
Guyot, M [1 ]
机构
[1] INST CHIM SUBST NAT,CNRS,F-91198 GIF SUR YVETTE,FRANCE
关键词
D O I
10.1016/0040-4039(96)00573-4
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A novel beta-carboline alkaloid, called hyrtiomanzamine, was isolated from the marine sponge Hyrtios erecta collected in the Red Sea Its structure elucidation was carried out by application of various one and two D NMR methods. Hyrtiomanzamine 1 is the first 6-OH-beta-carboline ring associated to a betaine unit isolated from the marine sponge Hyrtios erecta. Hyrtiomanzamine 1 showed immunosuppressive activity in the B lymphocytes reaction assay. Copyright (C) 1996 Elsevier Science Ltd
引用
收藏
页码:3457 / 3460
页数:4
相关论文
共 8 条
[1]   12-EPI-HETERONEMIN - NEW SESTERTERPENE FROM THE MARINE SPONGE HYRTIOS-ERECTA [J].
BOURGUETKONDRACKI, ML ;
MARTIN, MT ;
DEBITUS, C ;
GUYOT, M .
TETRAHEDRON LETTERS, 1994, 35 (01) :109-110
[2]   SESTERTERPENES FROM A COMMON MARINE SPONGE, HYRTIOS-ERECTA [J].
CREWS, P ;
BESCANSA, P .
JOURNAL OF NATURAL PRODUCTS, 1986, 49 (06) :1041-1052
[3]   C-13-NMR SPECTRUM AND STEREOCHEMISTRY OF HETERONEMIN [J].
KASHMAN, Y ;
RUDI, A .
TETRAHEDRON, 1977, 33 (22) :2997-2998
[4]  
KAZLAUSKAS R, 1976, Tetrahedron Letters, V30, P2631
[5]   4 NEW BETA-CARBOLINE ALKALOIDS ISOLATED FROM 2 OKINAWAN MARINE SPONGES OF XESTOSPONGIA SP AND HALICLONA SP [J].
KOBAYASHI, M ;
CHEN, YJ ;
AOKI, S ;
IN, Y ;
ISHIDA, T ;
KITAGAWA, I .
TETRAHEDRON, 1995, 51 (13) :3727-3736
[6]   DIDEMNOLINES A-D, NEW N9-SUBSTITUTED BETA-CARBOLINES FROM THE MARINE ASCIDIAN DIDEMNUM SP [J].
SCHUMACHER, RW ;
DAVIDSON, BS .
TETRAHEDRON, 1995, 51 (37) :10125-10130
[7]  
Scott A. I., 1964, INTERPRETATION ULTRA
[8]   NEW MARINE BETAINE, NORZOOANEMONIN, IN GORGONIAN PSEUDOPTEROGORGIA-AMERICANA [J].
WEINHEIMER, AJ ;
METZNER, EK ;
MOLE, ML .
TETRAHEDRON, 1973, 29 (20) :3135-3136