The sequences of seven class D β-lactamases isolated from carbapenem-resistant Acinetobacter baumannii from four continents

被引：79

作者：

Brown, S ^{[1
]}

Amyes, SGB ^{[1
]}

机构：

[1] Univ Edinburgh, Sch Med, Edinburgh EH8 9AG, Midlothian, Scotland

来源：

CLINICAL MICROBIOLOGY AND INFECTION | 2005年 / 11卷 / 04期

关键词：

Acinetobacter baumannii; beta-lactamase; carbapenemase; class D beta-lactamase; OXA carbapenenases; resistance;

D O I：

10.1111/j.1469-0691.2005.01096.x

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Carbapenem resistance associated with class D beta-lactamases is an increasing problem in Acinetobacter baumannii. Most enzymes of this class reported so far belong to two subgroups, 1 and 2; however, a novel class D carbapenemase (OXA-51) has been reported recently which shares 56% and < 63% amino-acid identity with subgroups 1 and 2, respectively, and which belongs to a third subgroup. This study describes a further seven novel subgroup 3 beta-lactamases in carbapenem-resistant A. baumannii isolates from four continents.

引用

页码：326 / 329

页数：4

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