Atherosclerosis and endothelial dysfunction in patients with ankylosing spondylitis

被引：30

作者：

Azevedo, V. F. ^{[1
]}

Pecoits-Filho, R. ^{[2
]}

机构：

[1] Univ Fed Parana, Spondylarthropathies Serv, BR-80250020 Reboucas Curitiba, PR, Brazil

[2] Pontificia Univ Catolica Parana, Grad Program Hlth Sci, Curitiba, Parana, Brazil

来源：

RHEUMATOLOGY INTERNATIONAL | 2010年 / 30卷 / 11期

关键词：

Spondylarthropathies; Ankylosing Spondylitis; Inflammation; Biomarkers; Cardiovascular disease; Atherosclerosis; Endothelial activation; Endothelial dysfunction; Arterial stiffness; STIMULATING ANGIOGENESIS FACTOR; INTIMA-MEDIA THICKNESS; CORONARY-HEART-DISEASE; RHEUMATOID-ARTHRITIS; CARDIOVASCULAR RISK; SUBCLINICAL ATHEROSCLEROSIS; CAPILLARY RECRUITMENT; CLINICAL-IMPLICATIONS; CHOLESTEROL LEVELS; FLOW RESERVE;

D O I：

10.1007/s00296-010-1416-3

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Ankylosing spondylitis (AS) is a systemic inflammatory rheumatic disease characterized primarily by axial joint involvement, sacroiliitis and various extra-articular manifestations. High cardiovascular mortality in AS has led many researchers to investigate possible risk factors involved with cardiovascular disease in these patients. This review summarizes published data concerning endothelial dysfunction and atherosclerosis in patients with AS. The author discusses current limitations and problems related to a better assessment of these two possible changes in AS.

引用

页码：1411 / 1416

页数：6

共 63 条

[1]

Amoroso A, 1997, Eur Rev Med Pharmacol Sci, V1, P17

[2]

BENJAMIN M, 2008, ANN RHEUM DIS 0714

[3]

Braun J, 2002, ANN RHEUM DIS, V61, P51

[4] First update of the international ASAS consensus statement for the use of anti-TNF agents in patients with ankylosing spondylitis [J].

Braun, J ;

Davis, J ;

Dougados, M ;

Sieper, J ;

van der Linden, S ;

van der Heijde, D .

ANNALS OF THE RHEUMATIC DISEASES, 2006, 65 (03) :316-320

[5]

Burger Danielle, 2002, Autoimmunity Reviews, V1, P111, DOI 10.1016/S1568-9972(01)00018-0

[6] Impaired coronary microvascular and left ventricular diastolic functions in patients with ankylosing spondylitis [J].

Caliskan, Mustafa ;

Erdogan, Dogan ;

Gullu, Hakan ;

Yilmaz, Sema ;

Gursoy, Yusuf ;

Yildirir, Aylin ;

Yucel, Eftal ;

Muderrisoglu, Haldun .

ATHEROSCLEROSIS, 2008, 196 (01) :306-312

[7] No differences of carotid intima-media thickness between young patients with ankylosing spondylitis and healthy controls [J].

Choe, Jung-Yoon ;

Lee, Myoung-Yong ;

Rheem, Insoo ;

Rhee, Moo-Yong ;

Park, Sung-Hoon ;

Kim, Seong-Kyu .

JOINT BONE SPINE, 2008, 75 (05) :548-553

[8] LONG-TERM MORTALITY AFTER A SINGLE TREATMENT COURSE WITH X-RAYS IN PATIENTS TREATED FOR ANKYLOSING-SPONDYLITIS [J].

DARBY, SC ;

DOLL, R ;

GILL, SK ;

SMITH, PG .

BRITISH JOURNAL OF CANCER, 1987, 55 (02) :179-190

[9] Visceral and truncal subcutaneous adipose tissue are associated with impaired capillary recruitment in healthy individuals [J].

de Jongh, Renate T. ;

Ijzerman, Richard G. ;

Serne, Erik H. ;

Voordouw, Jasper J. ;

Yudkin, John S. ;

Delemarre-van De Waal, Henriette A. ;

Stehouwer, Coen D. A. ;

van Weissenbruch, Mirjam M. .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2006, 91 (12) :5100-5106

[10] Endothelial function and dysfunction - Testing and clinical relevance [J].

Deanfield, John E. ;

Halcox, Julian P. ;

Rabelink, Ton J. .

CIRCULATION, 2007, 115 (10) :1285-1295

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