Controlling inflammation: a fat chance?

被引：34

作者：

Flower, RJ ^{[1
]}

Perretti, M ^{[1
]}

机构：

[1] William Harvey Res Inst, London EC1M 6BQ, England

来源：

JOURNAL OF EXPERIMENTAL MEDICINE | 2005年 / 201卷 / 05期

关键词：

D O I：

10.1084/jem.20050222

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The inflammatory response protects the body against infection and injury but can itself become deregulated with deleterious consequences to the host. It is now clear that several endogenous biochemical pathways activated during defense reactions can counterregulate inflammation. New experimental evidence adds resolvin E1 to this group of endogenous inhibitors and provides further rationale for the beneficial effects of dietary supplementation with fish oils. It also highlights an unexpected twist in the pharmacology of aspirin.

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页码：671 / 674

页数：4

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