Complete Hydatidiform Mole and Live Fetus in a Singleton Pregnancy with Confined Placental Mosaicism and Fetomaternal Hemorrhage A Case Report

被引:0
作者
Baxi, Laxmi V.
Mansukhani, Mahesh
Thaker, Harshwardhan M.
Parravicini, Elvira
机构
[1] NYU, Langone Med Ctr, Dept Obstet & Gynecol, New York, NY USA
[2] Columbia Univ, Med Ctr, Dept Pediat, New York, NY USA
[3] Columbia Univ, Med Ctr, Dept Pathol, New York, NY USA
关键词
confined placental mosaicism; fetomaternal hemorrhage; hydatidfform mole; molar pregnancy; molar pregnancy with coexisting live newborn; COEXISTING FETUS; CHORIOCARCINOMA;
D O I
暂无
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
BACKGROUND: Coexistence of complete mole and a live fetus is uncommon (1:22,000-100,000), more so with euploidy. CASE: We present a case of a molar pregnancy with a euploid fetus who had close fetal evaluation for second trimester bleeding. The patient presented at 29 weeks' gestation with decreased fetal movements, a result of fetomaternal hemorrhage. She underwent emergency cesarean section and delivered a live infant. By close follow-up and a multidisciplinary approach, the appropriate diagnosis and a favorable outcome were achieved. Both. mother and the child at 5 years of age are doing well. CONCLUSION: Detailed anatomic and molecular studies demonstrated a complete mole resulting from confined placental mosaicism, with molar tissue showing a single paternal allele at 8/8 'informative loci, all shared with the fetus, thus this coexistent molar pregnancy was not that of a separate conceptus.
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页码:599 / 602
页数:4
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