15 years of anti-VEGF treatment for nAMD: success or failure or something in between?

被引:19
作者
Chakravarthy, Usha [1 ]
Armendariz, Beatriz G. [2 ]
Fauser, Sascha [2 ]
机构
[1] Queens Univ Belfast, Inst Clin Sci, Royal Victoria Hosp, Ctr Publ Hlth, Belfast BT12 6BA, Antrim, North Ireland
[2] Roche Innovat Ctr Basel, Roche Pharma Res & Early Dev, Basel, Switzerland
关键词
MACULAR DEGENERATION; GEOGRAPHIC ATROPHY; OUTCOMES; GROWTH; RISK;
D O I
10.1038/s41433-022-02153-9
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
引用
收藏
页码:2232 / 2233
页数:2
相关论文
共 27 条
[1]  
[Anonymous], 2020, CAUSES VISION LOSS
[2]   Incidence of Legal Blindness From Age-Related Macular Degeneration in Denmark: Year 2000 to 2010 [J].
Bloch, Sara Brandi ;
Larsen, Michael ;
Munch, Inger Christine .
AMERICAN JOURNAL OF OPHTHALMOLOGY, 2012, 153 (02) :209-213
[3]   Experiences of patients undergoing repeated intravitreal anti-vascular endothelial growth factor injections for neovascular age-related macular degeneration [J].
Boyle, Jessica ;
Vukicevic, Meri ;
Koklanis, Konstandina ;
Itsiopoulos, Catherine ;
Rees, Gwyneth .
PSYCHOLOGY HEALTH & MEDICINE, 2018, 23 (02) :127-140
[4]   Tomographic Biomarkers Predicting Progression to Fibrosis in Treated Neovascular Age-Related Macular Degeneration: A Multimodal Imaging Study [J].
Casalino, Giuseppe ;
Stevenson, Michael R. ;
Bandello, Francesco ;
Chakravarthy, Usha .
OPHTHALMOLOGY RETINA, 2018, 2 (05) :451-461
[5]   Alternative treatments to inhibit VEGF in age-related choroidal neovascularisation: 2-year findings of the IVAN randomised controlled trial [J].
Chakravarthy, Usha ;
Harding, Simon P. ;
Rogers, Chris A. ;
Downes, Susan M. ;
Lotery, Andrew J. ;
Culliford, Lucy A. ;
Reeves, Barnaby C. .
LANCET, 2013, 382 (9900) :1258-1267
[6]   Lutein plus Zeaxanthin and Omega-3 Fatty Acids for Age-Related Macular Degeneration The Age-Related Eye Disease Study 2 (AREDS2) Randomized Clinical Trial [J].
Chew, Emily Y. ;
Clemons, Traci E. ;
SanGiovanni, John Paul ;
Danis, Ronald ;
Ferris, Frederick L., III ;
Elman, Michael ;
Antoszyk, Andrew ;
Ruby, Alan ;
Orth, David ;
Bressler, Susan ;
Fish, Gary ;
Hubbard, Baker ;
Klein, Michael ;
Chandra, Suresh ;
Blodi, Barbara ;
Domalpally, Amitha ;
Friberg, Thomas ;
Wong, Wai ;
Rosenfeld, Philip ;
Agron, Elvira ;
Toth, Cynthia ;
Bernstein, Paul ;
Sperduto, Robert .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2013, 309 (19) :2005-2015
[7]   Development and Course of Scars in the Comparison of Age-Related Macular Degeneration Treatments Trials [J].
Daniel, Ebenezer ;
Pan, Wei ;
Ying, Gui-shuang ;
Kim, Benjamin J. ;
Grunwald, Juan E. ;
Ferris, Frederick L., III ;
Jaffe, Glenn J. ;
Toth, Cynthia A. ;
Martin, Daniel F. ;
Fine, Stuart L. ;
Maguire, Maureen G. .
OPHTHALMOLOGY, 2018, 125 (07) :1037-1046
[8]   Risk of Scar in the Comparison of Age-related Macular Degeneration Treatments Trials [J].
Daniel, Ebenezer ;
Toth, Cynthia A. ;
Grunwald, Juan E. ;
Jaffe, Glenn J. ;
Martin, Daniel F. ;
Fine, Stuart L. ;
Huang, Jiayan ;
Ying, Gui-shuang ;
Hagstrom, Stephanie A. ;
Winter, Katrina ;
Maguire, Maureen G. .
OPHTHALMOLOGY, 2014, 121 (03) :656-666
[9]   Age-related macular degeneration: Epidemiology, genetics, pathophysiology, diagnosis, and targeted therapy [J].
Deng, Yanhui ;
Qiao, Lifeng ;
Du, Mingyan ;
Qu, Chao ;
Wan, Ling ;
Li, Jie ;
Huang, Lulin .
GENES & DISEASES, 2022, 9 (01) :62-79
[10]   HAWK and HARRIER: Phase 3, Multicenter, Randomized, Double-Masked Trials of Brolucizumab for Neovascular Age-Related Macular Degeneration [J].
Dugel, Pravin U. ;
Koh, Adrian ;
Ogura, Yuichiro ;
Jaffe, Glenn J. ;
Schmidt-Erfurth, Ursula ;
Brown, David M. ;
Gomes, Andre, V ;
Warburton, James ;
Weichselberger, Andreas ;
Holz, Frank G. .
OPHTHALMOLOGY, 2020, 127 (01) :72-84