Hepatocellular carcinoma in a case of adult-onset type II citrullinemia

被引：28
作者：
Hagiwara, N
Sekijima, Y
Takei, Y
Ikeda, S
Kawasaki, S
Kobayashi, K
Saheki, T
机构：
[1] Shinshu Univ, Sch Med, Dept Med 3, Matsumoto, Nagano 3908621, Japan
[2] Shinshu Univ, Sch Med, Dept Surg 1, Matsumoto, Nagano 3908621, Japan
[3] Kagoshima Univ, Fac Med, Dept Biochem, Kagoshima, Japan
来源：
INTERNAL MEDICINE | 2003年 / 42卷 / 10期
关键词：
citrulline; citrin; delivery; hepatocellular carcinoma; fatty change;
D O I：
10.2169/internalmedicine.42.978
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A 40-year-old woman was admitted with altered consciousness and hyperammonemia after she had delivered her first baby. DNA analysis of the citrin gene and enzymatic assay of argininosuccinate synthetase in the liver led to a diagnosis of adult-onset type II citrullinemia (CTLN2). She was also found to have hepatocellular carcinoma (HCC) and underwent palliative surgery consisting of partial liver section of the HCC. Delivery may be a trigger for the development of CTLN2, while certain pathologic conditions associated with citrin gene abnormality are likely to induce hepatocellular carcinoma in patients with this disorder.
引用
收藏
页码：978 / 982
页数：5
相关论文
共 50 条
[41]   Management of Large Hepatocellular Carcinoma in Adult Patients with Alagille Syndrome: A Case Report and Review of Literature [J].
Tsai, Susan ;
Gurakar, Ahmet ;
Anders, Robert ;
Lam-Himlin, Dora ;
Boitnott, John ;
Pawlik, Timothy M. .
DIGESTIVE DISEASES AND SCIENCES, 2010, 55 (11) :3052-3058
[42]   Late-onset diaphragmatic hernia after percutaneous radiofrequency ablation of hepatocellular carcinoma: a case study [J].
Tomoyuki Abe ;
Hironobu Amano ;
Hitomi Takechi ;
Nobuaki Fujikuni ;
Tatsunari Sasada ;
Makoto Yoshida ;
Minoru Yamaki ;
Masahiro Nakahara ;
Toshio Noriyuki .
Surgical Case Reports, 2 (1)
[43]   Late-onset benefit in progressive advanced hepatocellular carcinoma with continued sorafenib therapy: A case report [J].
Okuwaki Y. ;
Nakazawa T. ;
Hidaka H. ;
Shibuya A. ;
Koizumi W. .
Journal of Medical Case Reports, 6 (1)
[44]   Case report: A case of type 1 diabetes with diabetic ketoacidosis induced by envafolimab treatment in hepatocellular carcinoma [J].
Li, Youjia ;
Qu, Kai ;
Li, Xiuli ;
Yang, Xin ;
Zhang, Kanghuai ;
Xie, Jiao .
FRONTIERS IN IMMUNOLOGY, 2025, 16
[45]   Type II ground-glass hepatocytes as a marker of hepatocellular carcinoma in chronic hepatitis B [J].
Mathai, Alka Mary ;
Alexander, Jacob ;
Kuo, Fang-Ying ;
Torbenson, Michael ;
Swanson, Paul E. ;
Yeh, Matthew M. .
HUMAN PATHOLOGY, 2013, 44 (08) :1665-1671
[46]   Adrenocortical carcinoma mimicking hepatocellular carcinoma: A case report [J].
Ikeda, Takahiro ;
Kitasato, Amane ;
Okamoto, Tatsuya ;
Soeda, Momoko ;
Miura, Shiro ;
Kuroki, Tamotsu .
INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS, 2023, 105
[47]   A Rare Case Report: Carcinoma Pancreas with Hepatocellular Carcinoma [J].
Yadav, Vikas ;
Panda, Dipanjan ;
Patidar, Yashwant ;
Bihari, Chhagan .
INDIAN JOURNAL OF PALLIATIVE CARE, 2014, 20 (01) :53-56
[48]   Therapeutic Efficacy of Leukocytapheresis in a Pregnant Woman with Refractory Adult-onset Still's Disease [J].
Odai, Tsuyoshi ;
Isozaki, Takeo ;
Kasama, Tsuyoshi ;
Ogata, Hiroaki ;
Kinugasa, Eriko .
INTERNAL MEDICINE, 2015, 54 (17) :2261-2266
[49]   A case of hepatocellular carcinoma with marked hyperfibrinogenemia [J].
Amemiya, N ;
Yatomi, Y ;
Endo, T ;
Mizoe, A ;
YodaEndo, M ;
Yuminamochi, T ;
Yamamoto, M ;
Ozaki, Y ;
Kume, S .
ACTA HAEMATOLOGICA, 1997, 97 (04) :236-238
[50]   Hepatocellular carcinoma in pregnancy - A case report [J].
Gisi, P ;
Floyd, R .
JOURNAL OF REPRODUCTIVE MEDICINE, 1999, 44 (01) :65-67
12345