Amplification of G-quadruplex DNAzymes using PCR-like temperature cycles for specific nucleic acid and single nucleotide polymorphism detection

被引：46

作者：

Wang, Na ^{[1
]}

Kong, De-Ming ^{[1
]}

Shen, Han-Xi ^{[1
]}

机构：

[1] Nankai Univ, Key Lab Funct Polymer Mat, Minist Educ, Tianjin 300071, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 06期

关键词：

PEROXIDASE-ACTIVITY; AMPLIFIED DETECTION; DNA; CYSTEINE; PROBES; AG+;

D O I：

10.1039/c0cc04182c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A nucleic acid sensor, based on the amplified formation of G-quadruplex DNAzymes by polymerase chain reaction (PCR)-like temperature cycles, was developed. This "turn-on'' process allowed effective detection of specific nucleic acid targets and identification of single nucleotide polymorphisms (SNPs).

引用

页码：1728 / 1730

页数：3

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