Plasma N-tau-methylhistidine concentration is a sensitive index of myofibrillar protein degradation during starvation in rats

被引：56

作者：

Nagasawa, T ^{[1
]}

Yoshizawa, F ^{[1
]}

Nishizawa, N ^{[1
]}

机构：

[1] IWATE PREFECTURAL MORIOKA JR COLL, MORIOKA, IWATE 020, JAPAN

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 1996年 / 60卷 / 03期

关键词：

protein degradation; starvation; myofibrillar protein; 3-methylhistidine;

D O I：

10.1271/bbb.60.501

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Urinary excretion of N-tau-methylhistidine (MeHis) in rats was linearly elevated by starvation for 2 days. Plasma concentration of MeHis on day 1 and day 2 of starvation were increased 2.4- and 2.6-fold, respectively. The amount of released MeHis from the isolated muscles into medium during a 2-h incubation period was increased with starvation corresponded to the plasma MeHis concentration. The results of this study suggest that plasma MeHis is a sensitive index of myofibrillar protein degradation.

引用

页码：501 / 502

页数：2

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