Acute acalculous cholecystitis following COVID-19 vaccination: a case report

被引：3

作者：

Kyungu, Fabien Mukonki ^{[1
,2
]}

Katumba, Aude Mukonki ^{[3
]}

Kamwira, Hermann Luhavo ^{[2
]}

Mayikuli, Aime Vonda ^{[2
]}

Mala, Adou ^{[4
]}

Banza, Manix Ilunga ^{[5
]}

Manirou, Haladou Mahaman ^{[6
]}

Tosali, Fiston Bolanda ^{[7
]}

Mulenga, Philippe Cilundika ^{[3
]}

机构：

[1] Univ Lubumbashi, Fac Med, Dept Publ Hlth, Unit Occupat Med & Environm Res, Lubumbashi, DEM REP CONGO

[2] Barrick Gold Corp, Kibali Gold Mine, Occupat Hlth & Safety Dept, Doko, Haut Uele Provi, DEM REP CONGO

[3] Univ Lubumbashi, Fac Med, Dept Publ Hlth, Lubumbashi, DEM REP CONGO

[4] Inst Natl Rech Biomed, Goma, Province Du Nor, DEM REP CONGO

[5] Univ Lubumbashi, Fac Med, Dept Surg, Lubumbashi, DEM REP CONGO

[6] Barrick Gold Corp, Occupat Hlth & Safety Dept, Bamako, Mali

[7] Ctr Traitement COVID 19, Watsa, Province Du Hau, DEM REP CONGO

来源：

PAN AFRICAN MEDICAL JOURNAL | 2022年 / 41卷

关键词：

Acute acalculous cholecystitis; liver dysfunction; COVID-19; vaccination; case report; IMMUNIZATION PRACTICES; ADVISORY-COMMITTEE; UNITED-STATES;

D O I：

10.11604/pamj.2022.41.291.33047

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Acute acalculous cholecystitis is an acute inflammation of the gallbladder in the absence of stones, usually occurring in elderly and critically ill patients with underlying conditions. A 29-year-old man presented to the hospital complaining of abdominal pain in the right hypochondrium with permanent fever three days after Janssen COVID-19 vaccine inoculation. Abdominal ultrasound revealed a thickened gallbladder wall without evidence of gallstone consistent of an acute acalculous cholecystitis. Blood analyses revealed thrombocytopenia, eosinophilia and liver dysfunction. The Polymerase Chain Reaction (PCR) COVID-19 test was negative. As treatment, the patient benefited of pain management, antibiotic and fluid. In the evolution, there was a regression of clinical signs with persistence of liver dysfunction. The patient was discharged ten days after hospitalization. The Janssen COVID-19 vaccine is likely to induce acute acalculous cholecystitis as adverse event following vaccination.

引用

页数：6

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