Recurrent Laryngeal Nerve Monitoring and Rocuronium: A Selective Sugammadex Reversal Protocol

被引:25
作者
de Vendin, Ombeline Empis [1 ,3 ]
Schmartz, Denis [1 ,3 ]
Brunaud, Laurent [2 ,3 ]
Fuchs-Buder, Thomas [1 ,3 ]
机构
[1] CHRU Nancy, Dept Anesthesiol & Intens Care Med, Vandoeuvre Les Nancy, France
[2] CHRU Nancy, Dept Digest Hepatobiliary & Endocrine Surg, Vandoeuvre Les Nancy, France
[3] Univ Lorraine, Fac Med, Vandoeuvre Les Nancy, France
关键词
INDUCED NEUROMUSCULAR BLOCKADE; TRACHEAL INTUBATION; CONTROLLED-TRIAL; THYROID-SURGERY; ANESTHESIA;
D O I
10.1007/s00268-017-4004-9
中图分类号
R61 [外科手术学];
学科分类号
摘要
The use of neuromuscular blocking agents may affect intraoperative neuromonitoring during thyroid surgery. A selective neuromuscular recovery protocol was evaluated in a retrospective cohort study during human thyroid neural monitoring surgery. One hundred and twenty-five consecutive patients undergoing thyroidectomy with intraoperative neuromonitoring followed a selective neuromuscular block recovery protocol-single intubating dose of rocuronium followed by sugammadex if needed at the first vagal stimulation (V1). Data from 120 of 125 patients could be analysed. Fifteen (12.5%) patients needed sugammadex reversal to obtain an EMG response at the first vagal stimulation (V1). In the remaining 105 patients, spontaneous recovery of rocuronium-induced neuromuscular block was sufficient for a successful first vagal stimulation (V1). In patients undergoing thyroid surgery, routine reversal of rocuronium block with sugammadex is not mandatory for reliable intraoperative neuromonitoring. A selective neuromuscular block recovery approach may be a valuable and more cost-efficient alternative to routine reversal.
引用
收藏
页码:2298 / 2303
页数:6
相关论文
共 22 条
[1]   Reversal of rocuronium-induced neuromuscular blockade with sugammadex compared with neostigmine during sevoflurane anaesthesia: results of a randomised, controlled trial [J].
Blobner, Manfred ;
Eriksson, Lars I. ;
Scholz, Jens ;
Motsch, Johann ;
Della Rocca, Giorgio ;
Prins, Martine E. .
EUROPEAN JOURNAL OF ANAESTHESIOLOGY, 2010, 27 (10) :874-881
[2]   In Reference to Reversal of Rocuronium-Induced Neuromuscular Blockade by Sugammadex Allows for Optimization of Neural Monitoring of the Recurrent Laryngeal Nerve [J].
Brunaud, Laurent ;
Fuchs-Buder, Thomas .
LARYNGOSCOPE, 2017, 127 (01) :E50-E50
[3]   Comparison of two induction regimens using or not using muscle relaxant: Impact on postoperative upper airway discomfort [J].
Combes, X. ;
Andriamifady, L. ;
Dufresne, E. ;
Suen, P. ;
Sauvat, S. ;
Scherrer, E. ;
Feiss, P. ;
Martyr, J. ;
Duvaldestin, P. .
BRITISH JOURNAL OF ANAESTHESIA, 2007, 99 (02) :276-281
[4]   Predictors of the variability in neuromuscular block duration following succinylcholine A prospective, observational study [J].
Dell-Kuster, Salome ;
Levano, Soledad ;
Burkhart, Christoph S. ;
Lelais, Frederic ;
Zemp, Andre ;
Schobinger, Elektra ;
Hampl, Karl ;
Kindler, Christoph ;
Girard, Thierry .
EUROPEAN JOURNAL OF ANAESTHESIOLOGY, 2015, 32 (10) :687-696
[5]   Intraoperative monitoring of the recurrent laryngeal nerve in thyroid surgery [J].
Dralle, H. ;
Sekulla, C. ;
Lorenz, K. ;
Brauckhoff, M. ;
Machens, A. .
WORLD JOURNAL OF SURGERY, 2008, 32 (07) :1358-1366
[6]   Can residual paralysis be avoided? A critical appraisal of the use of sugammadex [J].
Esteves, Simao .
EUROPEAN JOURNAL OF ANAESTHESIOLOGY, 2015, 32 (10) :663-665
[7]   Does intraoperative nerve monitoring reliably aid in staging of total thyroidectomies? [J].
Fontenot, Tatyana E. ;
Randolph, Gregory W. ;
Setton, Tedhar E. ;
Alsaleh, Nuha ;
Kandil, Emad .
LARYNGOSCOPE, 2015, 125 (09) :2232-2235
[8]   Good clinical research practice in pharmacodynamic studies of neuromuscular blocking agents II: the Stockholm revision [J].
Fuchs-Buder, T. ;
Claudius, C. ;
Skovgaard, L. T. ;
Eriksson, L. I. ;
Mirakhur, R. K. ;
Viby-Mogensen, J. .
ACTA ANAESTHESIOLOGICA SCANDINAVICA, 2007, 51 (07) :789-808
[9]   Monitoring neuromuscular block: an update [J].
Fuchs-Buder, T. ;
Schreiber, J-U ;
Meistelman, C. .
ANAESTHESIA, 2009, 64 :82-89
[10]  
Fuchs-Buder T, 2013, KOREAN J ANESTHESIOL, V65, P495