Estrogen metabolism and breast cancer

被引：271

作者：

Samavat, Hamed ^{[1
]}

Kurzer, Mindy S. ^{[1
]}

机构：

[1] Univ Minnesota, Dept Food Sci & Nutr, St Paul, MN 55108 USA

来源：

CANCER LETTERS | 2015年 / 356卷 / 02期

基金：

美国国家卫生研究院;

关键词：

Breast cancer; Sex hormones; Estrogen; Estrogen metabolites; Postmenopausal women; Premenopausal women; CATECHOL-O-METHYLTRANSFERASE; SEX-HORMONE LEVELS; POSTMENOPAUSAL WOMEN; PREMENOPAUSAL WOMEN; DEHYDROEPIANDROSTERONE-SULFATE; GENETIC POLYMORPHISMS; ENDOGENOUS ESTROGENS; ESTRADIOL METABOLISM; MAMMOGRAPHIC DENSITY; METHYL TRANSFERASE;

D O I：

10.1016/j.canlet.2014.04.018

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

There is currently accumulating evidence that endogenous estrogens play a critical role in the development of breast cancer. Estrogens and their metabolites have been studied in both pre-and postmenopausal women with more consistent results shown in the latter population, in part because of large hormonal variations during the menstrual cycle and far fewer studies having been performed in premenopausal women. In this review we describe in detail estrogen metabolism and associated genetic variations, and provide a critical review of the current literature regarding the role of estrogens and their metabolites in breast cancer risk. (C) 2014 Elsevier Ireland Ltd. All rights reserved.

引用

页码：231 / 243

页数：13

共 146 条

[1]

Althuis MD, 2004, CANCER EPIDEM BIOMAR, V13, P1558

[2]

[Anonymous], WILLIAMS TXB ENDOCRI

[3]

[Anonymous], 2013, Breast Cancer Facts Figures 2013-2014

[4]

[Anonymous], HDB ENV CHEM L

[5] Circulating Estrogen Metabolites and Risk for Breast Cancer in Premenopausal Women [J].

Arslan, Alan A. ;

Shore, Roy E. ;

Afanasyeva, Yelena ;

Koenig, Karen L. ;

Toniolo, Paolo ;

Zeleniuch-Jacquotte, Anne .

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 2009, 18 (08) :2273-2279

[6] Circulating Steroid Hormone Levels and Risk of Breast Cancer for Postmenopausal Women [J].

Baglietto, Laura ;

Severi, Gianluca ;

English, Dallas R. ;

Krishnan, Kavitha ;

Hopper, John L. ;

McLean, Catriona ;

Morris, Howard A. ;

Tilley, Wayne D. ;

Giles, Graham G. .

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 2010, 19 (02) :492-502

[7]

BARRETTCONNOR E, 1990, CANCER RES, V50, P6571

[8] Endogenous sex hormones, breast cancer risk, and tamoxifen response: An ancillary study in the NSABP Breast Cancer Prevention Trial (P-1) [J].

Beattie, MS ;

Costantino, JP ;

Cummings, SR ;

Wickerham, DL ;

Vogel, VG ;

Dowsett, M ;

Folkerd, EJ ;

Willett, WC ;

Wolmark, N ;

Hankinson, SE .

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2006, 98 (02) :110-115

[9] Serum sex hormone levels after menopause and subsequent breast cancer [J].

Berrino, F ;

Muti, P ;

Micheli, A ;

Bolelli, G ;

Krogh, V ;

Sciajno, R ;

Pisani, P ;

Panico, S ;

Secreto, G .

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1996, 88 (05) :291-296

[10]

Bradlow HI, 1996, J ENDOCRINOL, V150, pS259

← 1 2 3 4 5 6 7 8 9 10 →