Immediate breast reconstruction with prostheses after conservative treatment plus intraoperative radiotherapy. Long term esthetic and oncological outcomes

被引:9
作者
De Lorenzi, Francesca [1 ]
Lohsiriwat, Visnu [1 ,2 ]
Barbieri, Benedetta [1 ]
Perez, Suanly Rodriguez [3 ]
Garusi, Cristina [1 ]
Petit, Jean Yves [1 ]
Galimberti, Viviana [3 ]
Rietjens, Mario [1 ]
机构
[1] European Inst Oncol, Dept Plast & Reconstruct Surg, I-20141 Milan, Italy
[2] Mahidol Univ, Dept Surg, Fac Med, Siriraj Hosp, Bangkok 10700, Thailand
[3] EIO, Dept Breast Surg, I-20141 Milan, Italy
关键词
Breast conservative treatment; Intraoperative radiotherapy; Breast cancer; Capsular contracture; Cancer recurrence; NIPPLE-SPARING MASTECTOMY; RADIATION-THERAPY; ELECTRONS ELIOT; CONSERVING THERAPY; INTERSTITIAL BRACHYTHERAPY; PATIENT SATISFACTION; CAPSULAR CONTRACTURE; SURGICAL TECHNIQUE; CANCER PATIENTS; IRRADIATION;
D O I
10.1016/j.breast.2012.03.006
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Electron intraoperative radiotherapy (ELIOT) has been introduced for breast conservative treatment (BCT) with promising oncological outcome. Thus, immediate breast reconstruction with prosthesis after BCT became possible due to minimal radiation effect on local tissue from ELIOT. We reported oncological and esthetical results of 29 BCT patients who had immediate implant reconstruction plus 21 Gy-ELIOT as the sole radiation treatment. All patients had prosthesis in ipsilateral breast and had simultaneous contralateral augmentation for symmetrical procedure. The average age was 52.3 years. There were stage la thirteen cases, stage Ib seven cases, stage Ila six cases and stage IIlb one case and two cases of intraepithelial neoplasia. From 54.2 (36-88) months follow up, the capsular contracture grading in the reconstructed breast from ELIOT-side is comparable with non-irradiated contralateral side. There was one patient who developed local recurrence (LR) and later on dead with breast related event (LR = 0.76% per year). There was no primary ipsilateral carcinomas and distant metastasis. (C) 2012 Elsevier Ltd. All rights reserved.
引用
收藏
页码:374 / 379
页数:6
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