Electron microscope analysis of cardiomyocytes in the rat left ventricle under simulation of weightlessness effects and artificial gravitation

被引：2

作者：

Varenik, E. N. ^{[1
]}

Lipina, T. V. ^{[1
]}

Shornikova, M. V. ^{[1
]}

Krasnov, I. B. ^{[2
]}

Chentsov, Yu. S. ^{[1
]}

机构：

[1] Moscow MV Lomonosov State Univ, Fac Biol, Vorobevy Gory Moscow 119991, Russia

[2] Russian Acad Sci, Inst Biol Med Problems, Moscow 123007, Russia

来源：

BIOLOGY BULLETIN | 2012年 / 39卷 / 03期

关键词：

Biology Bulletin; Electron Microscope Analysis; Artificial Gravity; Myocar Dium; Subsarcolemmal Region;

D O I：

10.1134/S1062359012030132

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Electron microscopic study of left ventricle cardiomyocytes and quantitative analysis of their mitochondriom was performed in rats exposed to tail-suspension, as a model of weightlessness effects, to artificial gravity produced by intermittent 2 centrifugation and a combination of these effects. It was found that the cardiomyocytes ultrastructure changed slightly after tail-suspension and after intermittent 2 influence, as well as under a combination of these effects. However, the number of intermitochondrial junctions increased significantly in the interfibrillar zone of cardiomyocytes under a combination of tail-suspension and intermittent 2 influence, which agrees with the cell hypertrophy described earlier.

引用

页码：221 / 228

页数：8

共 20 条

[1]

Agafonova EL, 1997, BIOL MEMBRANY, V14, P495

[2]

Bakeeva L.E., 1989, ITOGI NAUKI TEKHN OB, V9

[3]

Il'in E.A., 1984, KOSM BIOL AVIAK MED, P65

[4]

Lipina T.V., 2004, B EKSP BIOL MED, V137, P328

[5]

Meerson F.Z., 1988, ADAPTATSIYA K STRESS

[6] Hindlimb unloading rodent model: technical aspects [J].

Morey-Holton, ER ;

Globus, RK .

JOURNAL OF APPLIED PHYSIOLOGY, 2002, 92 (04) :1367-1377

[7]

MOREYHOLTON ER, 1981, PHYSIOLOGIST S, V24, P45

[8]

Nepomnyashchikh L.M., 2001, B EKSP BIOL MED, V131, P11

[9]

NIKOGOSOVA M O, 1991, Byulleten' Eksperimental'noi Biologii i Meditsiny, V111, P417

[10]

Palmer J.W., 1986, AM J PHYSIOL, V250, P741

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