Tissue engineering: strategies, stem cells and scaffolds

被引：339
作者：
Howard, Daniel [1 ]
Buttery, Lee D. [1 ]
Shakesheff, Kevin M. [1 ]
Roberts, Scott J. [1 ]
机构：
[1] Univ Nottingham, Sch Pharm, Ctr Biomol Sci, Wolfson Ctr Stem Cells Tissue Engn & Modelling, Nottingham NG7 2RD, England
来源：
JOURNAL OF ANATOMY | 2008年 / 213卷 / 01期
基金：
英国生物技术与生命科学研究理事会;
关键词：
controlled growth factor delivery; embryonic stem cells; injectable scaffolds; mesenchymal stem cells; regenerative medicine; surface engineering; tissue engineering; zonated scaffolds;
D O I：
10.1111/j.1469-7580.2008.00878.x
中图分类号：
R602 [外科病理学、解剖学]; R32 [人体形态学];
学科分类号：
100101 ;
摘要：
Tissue engineering scaffolds are designed to influence the physical, chemical and biological environment surrounding a cell population. In this review we focus on our own work and introduce a range of strategies and materials used for tissue engineering, including the sources of cells suitable for tissue engineering: embryonic stem cells, bone marrow-derived mesenchymal stem cells and cord-derived mesenchymal stem cells. Furthermore, we emphasize the developments in custom scaffold design and manufacture, highlighting laser sintering, supercritical carbon dioxide processing, growth factor incorporation and zoning, plasma modification of scaffold surfaces, and novel multi-use temperature-sensitive injectable materials.
引用
收藏
页码：66 / 72
页数：7
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