Cross-sectional associations between the gut microbe Ruminococcus gnavus and features of the metabolic syndrome

被引：53

作者：

Grahnemo, Louise ^{[1
]}

Nethander, Maria ^{[1
,2
]}

Coward, Eivind ^{[1
,3
]}

Gabrielsen, Maiken Elvestad ^{[3
]}

Sree, Satya ^{[4
]}

Billod, Jean-Marc ^{[4
]}

Engstrand, Lars ^{[5
]}

Abrahamsson, Sanna ^{[2
]}

Langhammer, Arnulf ^{[6
,7
]}

Hveem, Kristian ^{[3
,6
,7
]}

Ohlsson, Claes ^{[8
]}

机构：

[1] Sahlgrenska Osteoporosis Ctr, Ctr Bone & Arthrit Res, Dept Internal Med & Clin Nutr, Inst Med, S-41345 Gothenburg, Sweden

[2] Univ Gothenburg, Sahlgrenska Acad, Bioinformat Core Facil, S-41345 Gothenburg, Sweden

[3] Norwegian Univ Sci & Technol, Dept Publ Hlth & Nursing, KG Jebsen Ctr Genet Epidemiol, Trondheim, Norway

[4] Bio Me Sci Pk, Oslo, Norway

[5] Karolinska Hosp, Karolinska Inst, Dept Microbiol Tumor & Cell Biol, Ctr Translat Microbiome Res,Biomed A8, Stockholm, Sweden

[6] Norwegian Univ Sci & Technol, Dept Publ Hlth & Nursing, HUNT Res Ctr, Levanger, Norway

[7] Levanger Hosp, Nord Trondelag Hosp Trust, Levanger, Norway

[8] Sahlgrens Univ Hosp, Dept Drug Treatment, Gothenburg, Sweden

来源：

LANCET DIABETES & ENDOCRINOLOGY | 2022年 / 10卷 / 07期

基金：

瑞典研究理事会;

关键词：

BODY-MASS INDEX; OBESITY; DISEASE;

D O I：

10.1016/S2213-8587(22)00113-9

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：481 / 483

页数：3

共 10 条

[1] Microbiome connections with host metabolism and habitual diet from 1,098 deeply phenotyped individuals [J].

Asnicar, Francesco ;

Berry, Sarah E. ;

Valdes, Ana M. ;

Nguyen, Long H. ;

Piccinno, Gianmarco ;

Drew, David A. ;

Leeming, Emily ;

Gibson, Rachel ;

Le Roy, Caroline ;

Al Khatib, Haya ;

Francis, Lucy ;

Mazidi, Mohsen ;

Mompeo, Olatz ;

Valles-Colomer, Mireia ;

Tett, Adrian ;

Beghini, Francesco ;

Dubois, Leonard ;

Bazzani, Davide ;

Thomas, Andrew Maltez ;

Mirzayi, Chloe ;

Khleborodova, Asya ;

Oh, Sehyun ;

Hine, Rachel ;

Bonnett, Christopher ;

Capdevila, Joan ;

Danzanvilliers, Serge ;

Giordano, Francesca ;

Geistlinger, Ludwig ;

Waldron, Levi ;

Davies, Richard ;

Hadjigeorgiou, George ;

Wolf, Jonathan ;

Ordovas, Jose M. ;

Gardner, Christopher ;

Franks, Paul W. ;

Chan, Andrew T. ;

Huttenhower, Curtis ;

Spector, Tim D. ;

Segata, Nicola .

NATURE MEDICINE, 2021, 27 (02) :321-+

[2] Profile of the gut microbiota of adults with obesity: a systematic review [J].

Crovesy, Louise ;

Masterson, Daniele ;

Rosado, Eliane Lopes .

EUROPEAN JOURNAL OF CLINICAL NUTRITION, 2020, 74 (09) :1251-1262

[3] Ruminococcus gnavus, a member of the human gut microbiome associated with Crohn's disease, produces an inflammatory polysaccharide [J].

Henke, Matthew T. ;

Kenny, Douglas J. ;

Cassilly, Chelsi D. ;

Vlamakis, Hera ;

Xavier, Ramnik J. ;

Clardy, Jon .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 116 (26) :12672-12677

[4] Gut microbiota associations with common diseases and prescription medications in a population-based cohort [J].

Jackson, Matthew A. ;

Verdi, Serena ;

Maxan, Maria-Emanuela ;

Shin, Cheol Min ;

Zierer, Jonas ;

Bowyer, Ruth C. E. ;

Martin, Tiphaine ;

Williams, Frances M. K. ;

Menni, Cristina ;

Bell, Jordana T. ;

Spector, Tim D. ;

Steves, Claire J. .

NATURE COMMUNICATIONS, 2018, 9

[5] Genetic studies of body mass index yield new insights for obesity biology [J].

Locke, Adam E. ;

Kahali, Bratati ;

Berndt, Sonja I. ;

Justice, Anne E. ;

Pers, Tune H. ;

Day, Felix R. ;

Powell, Corey ;

Vedantam, Sailaja ;

Buchkovich, Martin L. ;

Yang, Jian ;

Croteau-Chonka, Damien C. ;

Esko, Tonu ;

Fall, Tove ;

Ferreira, Teresa ;

Gustafsson, Stefan ;

Kutalik, Zoltan ;

Luan, Jian'an ;

Maegi, Reedik ;

Randall, Joshua C. ;

Winkler, Thomas W. ;

Wood, Andrew R. ;

Workalemahu, Tsegaselassie ;

Faul, Jessica D. ;

Smith, Jennifer A. ;

Zhao, Jing Hua ;

Zhao, Wei ;

Chen, Jin ;

Fehrmann, Rudolf ;

Hedman, Asa K. ;

Karjalainen, Juha ;

Schmidt, Ellen M. ;

Absher, Devin ;

Amin, Najaf ;

Anderson, Denise ;

Beekman, Marian ;

Bolton, Jennifer L. ;

Bragg-Gresham, L. ;

Buyske, Steven ;

Demirkan, Ayse ;

Deng, Guohong ;

Ehret, Georg B. ;

Feenstra, Bjarke ;

Feitosa, Mary F. ;

Fischer, Krista ;

Goel, Anuj ;

Gong, Jian ;

Jackson, Anne U. ;

Kanoni, Stavroula ;

Kleber, Marcus E. ;

Kristiansson, Kati .

NATURE, 2015, 518 (7538) :197-+

[6] Metabolic mediators of the effects of body-mass index, overweight, and obesity on coronary heart disease and stroke: a pooled analysis of 97 prospective cohorts with 1.8 million participants [J].

Lu, Yuan ;

Hajifathalian, Kaveh ;

Ezzati, Majid ;

Woodward, Mark ;

Rimm, Eric B. ;

Danaei, Goodarz .

LANCET, 2014, 383 (9921) :970-983

[7] Mucolytic Bacteria With Increased Prevalence in IBD Mucosa Augment In Vitro Utilization of Mucin by Other Bacteria [J].

Png, Chin Wen ;

Linden, Sara K. ;

Gilshenan, Kristen S. ;

Zoetendal, Erwin G. ;

McSweeney, Chris S. ;

Sly, Lindsay I. ;

McGuckin, Michael A. ;

Florin, Timothy H. J. .

AMERICAN JOURNAL OF GASTROENTEROLOGY, 2010, 105 (11) :2420-2428

[8] Host variables confound gut microbiota studies of human disease [J].

Vujkovic-Cvijin, Ivan ;

Sklar, Jack ;

Jiang, Lingjing ;

Natarajan, Loki ;

Knight, Rob ;

Belkaid, Yasmine .

NATURE, 2020, 587 (7834) :448-+

[9] A Pyrosequencing Study in Twins Shows That Gastrointestinal Microbial Profiles Vary With Inflammatory Bowel Disease Phenotypes [J].

Willing, Ben P. ;

Dicksved, Johan ;

Halfvarson, Jonas ;

Andersson, Anders F. ;

Lucio, Marianna ;

Zheng, Zongli ;

Jarnerot, Gunnar ;

Tysk, Curt ;

Jansson, Janet K. ;

Engstrand, Lars .

GASTROENTEROLOGY, 2010, 139 (06) :1844-U105

[10] Bupleuri radix extract ameliorates impaired lipid metabolism in high-fat diet-induced obese mice via gut microbia-mediated regulation of FGF21 signaling pathway [J].

Wu, Liucen ;

Yan, Qian ;

Chen, Fenglian ;

Cao, Cheng ;

Wang, Shuling .

BIOMEDICINE & PHARMACOTHERAPY, 2021, 135

← 1 →