B cell memory and the long-lived plasma cell

被引:189
作者
McHeyzer-Williams, MG [1 ]
Ahmed, R
机构
[1] Duke Univ, Med Ctr, Dept Immunol, Durham, NC 27710 USA
[2] Emory Univ, Sch Med, Dept Microbiol & Immunol, Emory Vaccine Ctr, Atlanta, GA 30322 USA
关键词
D O I
10.1016/S0952-7915(99)80029-6
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The germinal center reaction is pivotal to the induction of B cell memory. The signals that regulate this complex microenvironment, with their cellular and molecular consequences, underpin long-term protective immunity. Recent studies have identified many key regulators of the germinal center cycle and have revealed an array of cellular outcomes that further define the memory B cell compartment.
引用
收藏
页码:172 / 179
页数:8
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