Pitfalls in the determination of mutant alleles of the thiopurine methyltransferase gene

被引:17
作者
Brouwer, C [1 ]
Marinaki, A [1 ]
Lambooy, L [1 ]
Duley, J [1 ]
Shobowale-Bakre, M [1 ]
De Abreu, RA [1 ]
机构
[1] UMC St Radboud, Dept Pediat, NL-6500 HB Nijmegen, Netherlands
关键词
D O I
10.1038/sj.leu.2402285
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:1792 / 1793
页数:2
相关论文
共 9 条
  • [1] Corominas H, 2000, AM J GASTROENTEROL, V95, P2313
  • [2] Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood acute lymphoblastic leukemia
    McLeod, HL
    Krynetski, EY
    Relling, MV
    Evans, WE
    [J]. LEUKEMIA, 2000, 14 (04) : 567 - 572
  • [3] Human thiopurine methyltransferase pharmacogenetics: Gene sequence polymorphisms
    Otterness, D
    Szumlanski, C
    Lennard, L
    Klemetsdal, B
    Aarbakke, J
    ParkHah, JO
    Iven, H
    Schmiegelow, K
    Branum, E
    OBrien, J
    Weinshilboum, R
    [J]. CLINICAL PHARMACOLOGY & THERAPEUTICS, 1997, 62 (01) : 60 - 73
  • [4] Schütz E, 2000, CLIN CHEM, V46, P1728
  • [5] Tai HL, 1996, AM J HUM GENET, V58, P694
  • [6] Enhanced proteolysis of thiopurine S-methyltransferase (TPMT) encoded by mutant alleles in humans (TPMT*3A, TPMT*2): Mechanisms for the genetic polymorphism of TPMT activity
    Tai, HL
    Krynetski, EY
    Schuetz, EG
    Yanishevski, Y
    Evans, WE
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (12) : 6444 - 6449
  • [7] Screening for azathioprine toxicity: A pharmacoeconomic analysis based on a target case
    Tavadia, SMB
    Mydlarski, PR
    Reis, MD
    Mittmann, N
    Pinkerton, PH
    Shear, N
    Sauder, DN
    [J]. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2000, 42 (04) : 628 - 632
  • [8] Thiopurine methyltransferase polymorphic tandem repeat: Genotype-phenotype correlation analysis
    Yan, L
    Zhang, SC
    Eiff, B
    Szumlanski, CL
    Powers, M
    O'Brien, JF
    Weinshilboum, RM
    [J]. CLINICAL PHARMACOLOGY & THERAPEUTICS, 2000, 68 (02) : 210 - 219
  • [9] Molecular diagnosis of thiopurine S-methyltransferase deficiency: Genetic basis for azathioprine and mercaptopurine intolerance
    Yates, CR
    Krynetski, EY
    Loennechen, T
    Fessing, MY
    Tai, HL
    Pui, CH
    Relling, MV
    Evans, WE
    [J]. ANNALS OF INTERNAL MEDICINE, 1997, 126 (08) : 608 - +