Ureas as new nucleophilic reagents for SNH amination and carbamoyl amination reactions in the 1,3,7-triazapyrene series

被引：9

作者：

Borovlev, Ivan V. ^{[1
]}

Demidov, Oleg P. ^{[1
]}

Amangasieva, Gulminat A. ^{[1
]}

Avakyan, Elena K. ^{[1
]}

Kurnosova, Nadezhda A. ^{[1
]}

机构：

[1] North Caucasus Fed Univ, Pushkin St 1, Stavropol 355009, Russia

来源：

ARKIVOC | 2016年

关键词：

Nucleophilic aromatic substitution of hydrogen; amination; carbamoyl amination; 1,3,7-triazapyren-6-amines; PALLADIUM-CATALYZED AMINATION; AROMATIC-SUBSTITUTION; HYDROLYSIS; ARYL; ALKOXYLATION; MECHANISM; HYDROGEN; NITROGEN;

D O I：

10.3998/ark.5550190.p009.412

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The ability of urea anions to react as nucleophiles with 1,3,7-triazapyrenes has been investigated. It was found that, against all expectations, the products of the substitution of hydrogen (S-N(H)) by an amino group were isolated in good yields. The reactions proceed in anhydrous DMSO solution at room temperature. However, when anions of mono substituted ureas containing bulky substituents were used, the products of previously unknown S-N(H) reactions of alkyl carbamoyl amination were obtained.

引用

页码：58 / 70

页数：13

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