Sinonasal Adenocarcinoma: A Rare Second Malignancy in Long Term Retinoblastoma Survivors

被引：3

作者：

Bhagia, Pooja ^{[1
]}

Colanta, Agnes Basas ^{[2
]}

Abramson, David H. ^{[3
]}

Carlson, Diane L. ^{[4
]}

Kleinerman, Ruth A. ^{[5
]}

Kraus, Dennis ^{[6
]}

Dunkel, Ira J. ^{[1
]}

机构：

[1] Mem Sloan Kettering Canc Ctr, Dept Pediat, New York, NY 10065 USA

[2] Mem Sloan Kettering Canc Ctr, Dept Pathol, New York, NY 10021 USA

[3] Mem Sloan Kettering Canc Ctr, Ophthalm Oncol Serv, New York, NY 10021 USA

[4] Cleveland Clin, Director Breast & Head & Neck Pathol, New York, NY USA

[5] NCI, Div Canc Epidemiol & Genet, New York, NY USA

[6] Mem Sloan Kettering Canc Ctr, Dept Surg, New York, NY 10021 USA

来源：

PEDIATRIC BLOOD & CANCER | 2011年 / 57卷 / 04期

基金：

美国国家卫生研究院;

关键词：

retinoblastoma; sinonasal adenocarcinoma; second malignancy; BILATERAL RETINOBLASTOMA; NONOCULAR TUMORS; CHILDHOOD-CANCER; FOLLOW-UP; RISK; RADIOTHERAPY;

D O I：

10.1002/pbc.23161

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Retinoblastoma is the most common primary cancer of the eye in children. The incidence of second tumors in survivors of bilateral retinoblastoma and in survivors of unilateral retinoblastoma who presumably carry a germline RB1 mutation is documented. This article describes the previously unrecognized association of sinonasal adenocarcinoma as a second malignancy in retinoblastoma Key words: retinoblastoma; sinonasal survivors. We present three cases who received radiation therapy as a part of their treatment and developed sinonasal adenocarcinoma as a second malignancy. Sinonasal adenocarcinoma should be considered as a second malignancy in retinoblastoma survivors who present with vague sinus symptoms. Pediatr Blood Cancer 2011; 57:693-695. (C) 2011 Wiley-Liss, Inc.

引用

页码：693 / 695

页数：3

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