PARP-1 drives slumber: A reciprocal relationship between sleep homeostasis and DNA damage repair

被引：5
|
作者：
Schibler, Ueli [1 ]
机构：
[1] Univ Geneva, Dept Mol Biol, CH-1211 Geneva 4, Switzerland
来源：
MOLECULAR CELL | 2021年 / 81卷 / 24期
关键词：
D O I：
10.1016/j.molcel.2021.11.028
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Sleep-wake cycles are orchestrated by the circadian clock and a sleep homeostat that records accumulating sleep pressure. Zada et al. (2021) now show that DNA lesions, recognized by PARP-1, accumulate in neurons of zebrafish larvae and promote homeostatic sleep pressure. © 2021 Elsevier Inc.
引用
收藏
页码：4958 / 4959
页数：2
相关论文
共 50 条
  • [1] PARP-1 regulates DNA repair factor availability
    Schiewer, Matthew J.
    Mandigo, Amy C.
    Gordon, Nicolas
    Huang, Fangjin
    Gaur, Sanchaika
    de Leeuw, Renee
    Zhao, Shuang G.
    Evans, Joseph
    Han, Sumin
    Parsons, Theodore
    Birbe, Ruth
    McCue, Peter
    McNair, Christopher
    Chand, Saswati N.
    Cendon-Florez, Ylenia
    Gallagher, Peter
    McCann, Jennifer J.
    Neupane, Neermala Poudel
    Shafi, Ayesha A.
    Dylgjeri, Emanuela
    Brand, Lucas J.
    Visakorpi, Tapio
    Raj, Ganesh V.
    Lallas, Costas D.
    Trabulsi, Edouard J.
    Gomella, Leonard G.
    Dicker, Adam P.
    Kelly, Wm. Kevin
    Leiby, Benjamin E.
    Knudsen, Beatrice
    Feng, Felix Y.
    Knudsen, Karen E.
    EMBO MOLECULAR MEDICINE, 2018, 10 (12)
  • [2] Rapid Detection and Signaling of DNA Damage by PARP-1
    Pandey, Nootan
    Black, Ben E.
    TRENDS IN BIOCHEMICAL SCIENCES, 2021, 46 (09) : 744 - 757
  • [3] PARP-1 is involved in autophagy induced by DNA damage
    Munoz-Gomez, Jose Antonio
    Rodriguez-Vargas, Jose Manuel
    Quiles-Perez, Rosa
    Aguilar-Quesada, Rocio
    Martin-Oliva, David
    de Murcia, Gilbert
    de Murcia, Josiane Menissier
    Almendros, Antonio
    de Almodovar, Mariano Ruiz
    Oliver, F. Javier
    AUTOPHAGY, 2009, 5 (01) : 61 - 74
  • [4] The comings and goings of PARP-1 in response to DNA damage
    Pascal, John M.
    DNA REPAIR, 2018, 71 : 177 - 182
  • [5] S-sulfhydration of MEK1 leads to PARP-1 activation and DNA damage repair
    Zhao, Kexin
    Ju, YoungJun
    Li, Shuangshuang
    Altaany, Zaid
    Wang, Rui
    Yang, Guangdong
    EMBO REPORTS, 2014, 15 (07) : 792 - 800
  • [6] Repair pathway for PARP-1 DNA-protein crosslinks
    Prasad, Rajendra
    Horton, Julie K.
    Dai, Da-Peng
    Wilson, Samuel H.
    DNA REPAIR, 2019, 73 : 71 - 77
  • [7] PARP-1 regulation of DNA repair factor availability.
    Schiewer, Matthew Joseph
    Mandigo, Amy C.
    Gordon, Nicolas
    McNair, Christopher
    Lallas, Costas D.
    Trabulsi, Edouard John
    Leiby, Benjamin
    Knudsen, Karen E.
    JOURNAL OF CLINICAL ONCOLOGY, 2019, 37 (07)
  • [8] PARP-1 and its associated nucleases in DNA damage response
    Wang, Yijie
    Luo, Weibo
    Wang, Yingfei
    DNA REPAIR, 2019, 81
  • [9] PARP-1, a determinant of cell survival in response to DNA damage
    Bouchard, WJ
    Rouleau, M
    Poirier, GG
    EXPERIMENTAL HEMATOLOGY, 2003, 31 (06) : 446 - 454
  • [10] PARP-1 dependent DNA damage repair and formation of reactive oxygen species in response to ionizing radiation
    Cieslar-Pobuda, A.
    Saenko, Y.
    Byczek, A.
    Rzeszowska-Wolny, J.
    EJC SUPPLEMENTS, 2010, 8 (05): : 212 - 212
12345