Splitting of α-Helical Structure as Molecular Basis for Abolishing an Amyloid Formation by Multiple Glycosylation: A Molecular Dynamics Simulation Study

被引:1
作者
Choi, Youngjin [1 ,2 ]
Cho, Eunae [3 ]
Jung, Seunho [3 ,4 ]
机构
[1] Hoseo Univ, BioChip Res Ctr, Dept Food Sci, Asan 31499, South Korea
[2] Hoseo Univ, BioChip Res Ctr, Dept Technol, Asan 31499, South Korea
[3] Konkuk Univ, Inst Ubiquitous Informat Technol & Applicat UBITA, CBRU, Seoul 05029, South Korea
[4] Konkuk Univ, MCRB, Dept Biosci & Biotechnol, Seoul 05029, South Korea
基金
新加坡国家研究基金会;
关键词
Amyloid formation; Glycosylation; Helical splitting; Molecular design; Sugar-bridge; O-GLCNAC; PHOSPHORYLATION; GALACTOSYLATION; DISEASES; IGG;
D O I
10.1002/bkcs.10832
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
[No abstract available]
引用
收藏
页码:1159 / 1162
页数:4
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