A Novel Taxane 13-Glucoside and Other Taxanes from the Leaves of Taxus cuspidata

被引：6

作者：

Ni, Zhi-Yu ^{[1
,2
]}

Dong, Mei ^{[1
,2
]}

Cong, Bin ^{[2
]}

Sauriol, Francoise ^{[3
]}

Zhang, Man-Li ^{[1
]}

Wang, Yu-Fang ^{[1
]}

Huo, Chang-Hong ^{[1
]}

Shi, Qing-Wen ^{[1
]}

Kiyota, Hiromasa ^{[4
]}

机构：

[1] Hebei Med Univ, Dept Med Nat Prod Chem, Sch Pharmaceut Sci, Shijiazhuang 050017, Hebei Province, Peoples R China

[2] Hebei Med Univ, Coll Basic Med, Shijiazhuang 050017, Hebei Province, Peoples R China

[3] Queens Univ, Dept Chem, Kingston, ON K7L 3N6, Canada

[4] Tohoku Univ, Grad Sch Agr Sci, Sendai, Miyagi 9818555, Japan

来源：

PLANTA MEDICA | 2011年 / 77卷 / 03期

关键词：

Taxus cuspidata; Taxaceae; taxanes; taxane glucoside; yew; leaves; CHINENSIS VAR. MAIREI; JAPANESE YEW; NEEDLES; DITERPENOIDS; TAXOIDS; SEEDS; BARK;

D O I：

10.1055/s-0030-1250333

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Three new taxanes, 2 alpha, 9 alpha, 10 beta-triacetoxy-13 alpha-(beta-D-glucopyranosyloxy)taxa-4(20), 11-dien-5 alpha-ol (1), 5 alpha, 10 beta, 13 alpha-triacetoxytax-11-ene-2 alpha,7 beta,9 alpha,20-tetraol (2), and 5 alpha, 10 beta, 13 beta-triacetoxy-2 alpha, 7 beta-dihydroxy-2(3 -> 20)abeotaxa-4(20), 11-dien-9-one (3), were isolated from the leaves of the Japanese yew, Taxus cuspidata. Compound 1 is the first example of a taxane with 13-glycosidic linkage.

引用

页码：281 / 283

页数：3

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