Alcohol consumption as a risk factor for pneumonia: a systematic review and meta-analysis

被引：110

作者：

Samokhvalov, A. V. ^{[1
]}

Irving, H. M. ^{[1
]}

Rehm, J. ^{[1
,2
,3
]}

机构：

[1] Ctr Addict & Mental Hlth, Toronto, ON M5S 2S1, Canada

[2] Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON M5S 1A1, Canada

[3] Tech Univ Dresden, Epidemiol Res Unit, Klin Psychol & Psychotherapie, Dresden, Germany

来源：

EPIDEMIOLOGY AND INFECTION | 2010年 / 138卷 / 12期

关键词：

Alcohol; alcohol dependence; causality; heavy drinking; pneumonia; COMMUNITY-ACQUIRED PNEUMONIA; BACTERIAL-INFECTION; TREND ESTIMATION; GUIDELINES; IMMUNITY;

D O I：

10.1017/S0950268810000774

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The aim of this study was to quantify the association between alcohol consumption and incidence of pneumonia and to examine possible pathways. This was done by a systematic review and meta-analyses on the dose-response relationship between alcohol consumption or alcohol-use disorders and the incidence of community-acquired pneumonia (CAP). The relative risk (RR) of CAP increased monotonically with increasing alcohol consumption. Individuals consuming 24, 60, and 120 g of pure alcohol daily demonstrated RRs for incident CAP of 1.12 (95% CI 1.02-1.23), 1.33 (95% CI 1.06-1.67) and 1.76 (95% CI 1.13-2.77), respectively, relative to non-drinkers. Clinically defined alcohol-use disorders were associated with an eightfold increased risk of CAP (RR 8.22, 95% CI 4.85-13.95). In conclusion, alcohol was found to be a risk factor for pneumonia with a clear statistical association, and a monotonic dose-response relationship.

引用

页码：1789 / 1795

页数：7

共 30 条

[1] New evidence of risk factors for community-acquired pneumonia:: a population-based study [J].

Almirall, J. ;

Bolibar, I. ;

Serra-Prat, M. ;

Roig, J. ;

Hospital, I. ;

Carandell, E. ;

Agusti, M. ;

Ayuso, P. ;

Estela, A. ;

Torres, A. .

EUROPEAN RESPIRATORY JOURNAL, 2008, 31 (06) :1274-1284

[2] Risk factors for community-acquired pneumonia in adults:: a population-based case-control study [J].

Almirall, J ;

Bolíbar, I ;

Balanzó, X ;

González, CA .

EUROPEAN RESPIRATORY JOURNAL, 1999, 13 (02) :349-355

[3]

[Anonymous], REL 10 1

[4]

[Anonymous], 2008, Multivariable model-building: a pragmatic approach to regression analysis based on fractional polynomials for modelling continuous variables

[5] A prospective study of age and lifestyle factors in relation to community-acquired pneumonia in US men and women [J].

Baik, I ;

Curhan, GC ;

Rimm, EB ;

Bendich, A ;

Willett, WC ;

Fawzi, WW .

ARCHIVES OF INTERNAL MEDICINE, 2000, 160 (20) :3082-3088

[6] Alcohol withdrawal syndrome: Turning minor injuries into a major problem [J].

Bard, Michael R. ;

Goettler, Claudia E. ;

Toschlog, Eric A. ;

Sagraves, Scott G. ;

Schenarts, Paul J. ;

Newell, Mark A. ;

Fugate, Mark ;

Rotondo, Michael F. .

JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 2006, 61 (06) :1441-1445

[7] OPERATING CHARACTERISTICS OF A BANK CORRELATION TEST FOR PUBLICATION BIAS [J].

BEGG, CB ;

MAZUMDAR, M .

BIOMETRICS, 1994, 50 (04) :1088-1101

[8] METAANALYSIS IN CLINICAL-TRIALS [J].

DERSIMONIAN, R ;

LAIRD, N .

CONTROLLED CLINICAL TRIALS, 1986, 7 (03) :177-188

[9] Bias in meta-analysis detected by a simple, graphical test [J].

Egger, M ;

Smith, GD ;

Schneider, M ;

Minder, C .

BMJ-BRITISH MEDICAL JOURNAL, 1997, 315 (7109) :629-634

[10] HIGH ALCOHOL INTAKE AS A RISK AND PROGNOSTIC FACTOR FOR COMMUNITY-ACQUIRED PNEUMONIA [J].

FERNANDEZSOLA, J ;

JUNQUE, A ;

ESTRUCH, R ;

MONFORTE, R ;

TORRES, A ;

URBANOMARQUEZ, A .

ARCHIVES OF INTERNAL MEDICINE, 1995, 155 (15) :1649-1654

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