Immediate- and medium-term effects of simultaneous percutaneous corrections of secundum type atrial septal defect combined with pulmonary valve stenosis. in local anesthesia and without transesophageal echocardiography guidance

被引:2
作者
Xu, Xu-Dong [1 ]
Ding, Xue-Yan [2 ]
Liu, Su-Xuan [1 ]
Bai, Yuan [1 ]
Zhao, Xian-Xian [1 ]
Qin, Yong-Wen [1 ]
机构
[1] Second Mil Med Univ, Dept Cardiol, Changhai Hosp, Shanghai 200433, Peoples R China
[2] 117 Hosp Chinese Peoples Liberat Army, Cardiovasc Therapeut Ctr, Hangzhou 310007, Zhejiang, Peoples R China
关键词
Transcatheter; Atrial septal defect; Congenital heart disease; Combined cardiopathies; Pulmonary stenosis; TRANSCATHETER CLOSURE; BALLOON VALVULOPLASTY; ADULT PATIENTS; AGE;
D O I
10.1016/j.jjcc.2014.03.014
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: The feasibility and efficacy of simultaneous percutaneous treatment of secundum type atrial septal defect (ASD) combined with pulmonary valve stenosis (PS) have not been proved. Objective: To evaluate the safety and efficacy on the clinical benefit of simultaneous percutaneous correction of these two pathologies under local anesthesia and without transesophageal echocardiography guidance. Methods: Transpulmonary gradient, functional status, pulmonary regurgitation (PR), and tricuspid regurgitation (TR) were studied in 35 patients undergoing percutaneous balloon pulmonary valvuloplasty and ASD closure from March 2004 to July 2012. All patients were followed up until January 2013, an average of 39 months. Results: According to color Doppler transthoracic echocardiography (HE) before the intervention, the ASD defect size and transpulmonary gradient were 17 +/- 8.4 mm and 88 +/- 37.8 mmHg, respectively. Postinterventionally, the peak-to-peak transpulmonary gradient decreased from 77 +/- 37.6 mmHg to 20 +/- 16.2 mmHg (p < 0.001) and the ASD occluder size was 23 +/- 10.5 mm. In all those patients, there was no residual shunt detected, and moderate and severe TR decreased from 45.7% (16/35) and 20% (7/35) to 8.6% (3/35) and 5.7% (2/35) before and after intervention detected by TTE, respectively. Eight patients had mild PR after procedure and two of them recovered at 6 months and no patient encountered severe adverse events at the latest follow-up. Conclusion: Simultaneous percutaneous corrections of ASD combined with PS are feasible, safe, and effective with satisfactory results. (C) 2014 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:32 / 36
页数:5
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