Convenient method for synthesis of chiral C1-symmetric pyrrolidine derivative

被引：0

作者：

Arif, Khaja Md. ^{[1
]}

机构：

[1] Govt Degree & PG Coll, Jammikunta 505122, Karimnagar, India

来源：

INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 2017年 / 56卷 / 08期

关键词：

Asymmetric transformations; pyrrolidine derivatives; C-1-symmetric; diasteteomers separation; chiral allenes; ENANTIOSELECTIVE SYNTHESIS; YLIDE ROUTE; LIGANDS; ALLENES;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Pyrrolidine derivatives are saturated N-heterocyclic compounds widely present in a large number of natural products, alkaloids and biologically active compounds. In this article, is reported the facile synthesis of chiral C-1-symmetric (S)-2-(anthracen-10-y1)-14(R)-1-phenylethy)pyrrolidine and (R)-2(anthracen-10-y1)-14(S)-1-phenylethyl)pyrrolidine diastereomers. These pyrrolidine derivatives are extremely useful for asymmetric transformations and enantioselective synthesis of chiral allenes.

引用

页码：897 / 899

页数：3

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