Mono-acylation of a polyamine-β-cyclodextrin based on guest mediated acyl migration

被引：10

作者：

Gomez-Biagi, Rodolfo F. ^{[1
]}

Nitz, Mark ^{[1
]}

机构：

[1] Univ Toronto, Dept Chem, Toronto, ON M5S 1A1, Canada

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 30期

基金：

加拿大自然科学与工程研究理事会;

关键词：

ALPHA-CYCLODEXTRINS; RECOGNITION;

D O I：

10.1039/c1cc12646f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The S -> N acylation rates of thioester functionalized coumarins on heptakis-[6-deoxy-6-(2-aminoethylsulfanyl)]-beta-cyclodextrin were measured. A high yield of mono-acylation was achieved with products that form self-inclusion compounds. The differential fluorescence response of the functionalized cyclodextrins upon binding biomacromolecules shows the potential of the constructs as probes.

引用

页码：8614 / 8616

页数：3

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