Biobehavioral Pathways to Cancer Incidence, Progression, and Quality of Life

被引:11
作者
Fagundes, Christopher P. [1 ,2 ,3 ]
Murdock, Kyle W. [1 ]
Chirinos, Diana A. [1 ]
Green, Paige A. [4 ]
机构
[1] Rice Univ, Dept Psychol, Houston, TX 77251 USA
[2] Univ Texas MD Anderson Canc Ctr, Dept Behav Sci, Houston, TX 77005 USA
[3] Baylor Coll Med, Dept Psychiat, Houston, TX 77030 USA
[4] NCI, Div Canc Control & Populat Sci, Bethesda, MD 20892 USA
关键词
psychoneuroimmunology; cancer; inflammation; HPA axis; autonomic nervous system; BREAST-CANCER; DNA-REPAIR; STRESS; APOPTOSIS; FATIGUE; SYSTEM; CELLS; RISK; GLUCOCORTICOIDS; INFLAMMATION;
D O I
10.1177/0963721417720958
中图分类号
B84 [心理学];
学科分类号
04 ; 0402 ;
摘要
Cancer research within the fields of psychoneuroendocrinology and psychoneuroimmunology has made substantial progress in understanding how psychological factors impact cancer. Although the pathways by which stress gets under the skin to impact cancer incidence, progression, and quality of life are not yet fully understood, the answers to key questions about how stressful life events and the negative emotions they generate can impact cancer initiation, progression, and survivorship have advanced quite dramatically. In this review, we summarize the state of the science in a way that is accessible to a broad audience. We then discuss future directions in cancer research, with a focus on ways psychological science can contribute to the next generation of cancer care.
引用
收藏
页码:548 / 553
页数:6
相关论文
共 36 条
[1]  
[Anonymous], 2015, Williams Textbook of Endocrinology E-Book
[2]   Anti-inflammatory actions of glucocorticoids: molecular mechanisms [J].
Barnes, PJ .
CLINICAL SCIENCE, 1998, 94 (06) :557-572
[3]   Cancer-related fatigue: Links with inflammation in cancer patients and survivors [J].
Bower, Julienne E. .
BRAIN BEHAVIOR AND IMMUNITY, 2007, 21 (07) :863-871
[4]   Childhood Adversity and Cumulative Life Stress: Risk Factors for Cancer-Related Fatigue [J].
Bower, Julienne E. ;
Crosswell, Alexandra D. ;
Slavich, George M. .
CLINICAL PSYCHOLOGICAL SCIENCE, 2014, 2 (01) :108-115
[5]   Inflammation and cancer-related fatigue: Mechanisms, contributing factors, and treatment implications [J].
Bower, Julienne E. ;
Lamkin, Donald M. .
BRAIN BEHAVIOR AND IMMUNITY, 2013, 30 :S48-S57
[6]   Cytokine modulation by glucocorticoids: Mechanisms and actions in cellular studies [J].
Brattsand, R ;
Linden, M .
ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 1996, 10 :81-90
[7]   DNA repair capacity in healthy medical students during and after exam stress [J].
Cohen, L ;
Marshall, GD ;
Cheng, L ;
Agarwal, SK ;
Wei, QY .
JOURNAL OF BEHAVIORAL MEDICINE, 2000, 23 (06) :531-544
[8]   Sympathetic nervous system regulation of the tumour microenvironment [J].
Cole, Steven W. ;
Nagaraja, Archana S. ;
Lutgendorf, Susan K. ;
Green, Paige A. ;
Sood, Anil K. .
NATURE REVIEWS CANCER, 2015, 15 (09) :563-572
[9]   Inflammatory biomarkers for persistent fatigue in breast cancer survivors [J].
Collado-Hidalgo, A ;
Bower, JE ;
Ganz, PA ;
Cole, SW ;
Irwin, MR .
CLINICAL CANCER RESEARCH, 2006, 12 (09) :2759-2766
[10]   Cancer Immunotherapy [J].
Couzin-Frankel, Jennifer .
SCIENCE, 2013, 342 (6165) :1432-1433