Posttraumatic stress disorder with secondary psychotic features: neurobiological findings

被引：6

作者：

Braakman, Mario H. ^{[1
]}

Kortmann, Frank A. M. ^{[1
]}

van den Brink, Wim ^{[1
]}

Verkes, Robbert J. ^{[1
]}

机构：

[1] Inst Mental Hlth Care, Wolfheze, Netherlands

来源：

STRESS HORMONES AND POST TRAUMATIC STRESS DISORDER: BASIC STUDIES AND CLINICAL PERSPECTIVES | 2007年 / 167卷

关键词：

PTSD; psychosis; PTSD-SP; neurobiology; corticotrophin releasing hormone (CRH); cortisol; dopamine beta-hydroxylase (DbH); smooth pursuit eye movement (SPEM);

D O I：

10.1016/S0079-6123(07)67027-7

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

The neurobiological knowledge on the potentially new diagnostic entity "posttraumatic stress disorder with secondary psychotic features" (PTSD-SP) is reviewed. Studies published between 1980 and 2006 were traced focussing on adult patients suffering from this "syndrome". Studies on cortisol, corticotrophin releasing hormone, dopamine beta-hydroxylase, smooth pursuit eye movements and psychopharmacology are described and potential pathophysiological mechanisms briefly discussed. More research is needed to validate the nosological status of PTSD-SP in order to promote neurobiological research and adequate therapeutic interventions.

引用

页码：299 / 302

页数：4

共 9 条

[1]

BRAAKMAN MH, UNPUB REV EVIDENCE

[2] Differences in smooth pursuit eye movement between posttraumatic stress disorder with secondary psychotic symptoms and schizophrenia [J].